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The Beaumont offline adaptive RT approach

Yan et al. 2000: An off-line strategy for constructing a patient-specific planning target volume

in adaptive treatment process for prostate cancer. IJROBP 48(1)

Martinez et al. 2001: Improvement in dose escalation using the process of adaptive

radiotherapy combined with three- dimensional conformal or intensity-modulated beams for

prostate cancer. IJROBP 50(5)

First systematic clinical adaptive RT implementation

at Beaumont Hospital, Royal Oak, Michigan: since 1997!

this is why it is called

‘offline’

!

ESTRO IMRT course 2016

Adaptive Radiotherapy

London April 7th, 2016

-24-

planning

CT

(IMRT)

plan

1 cm margin

around CTV

PI,

CT

Fx

5

Fx

1

Fx

6

estimation of

systematic setup

error

, characterization of

internal organ motion

new isocentre

new plan

Fx

N

PI,

CT

(IMRT)

plan

new, adapted

PTV: ‘cl-PTV’