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The next step: more than one re-optimization,

dose accumulation, probabilistic planning

planning

CT

IMRT

plan

Fx

5

Fx

1

Fx

6

Fx

N

M. Birkner et al. 2003: Adapting inverse planning to patient and organ geometrical

variation: algorithm and implementation.

Med. Phys. 30(10)

one feedback loop

ESTRO IMRT course 2016

Adaptive Radiotherapy

London April 7th, 2016

-28-

1 cm margin

around CTV

CT

CT

deformable registration,

dose warping,

dose accumulation

model motion of each voxel, this

enables calculation of average

‘expected’ dose-per-voxel

probabilistic

IMRT

plan

new plan

optimizes the expected

dose-per-voxel