The next step: more than one re-optimization,
dose accumulation, probabilistic planning
planning
CT
IMRT
plan
…
Fx
5
Fx
1
Fx
6
Fx
N
…
M. Birkner et al. 2003: Adapting inverse planning to patient and organ geometrical
variation: algorithm and implementation.
Med. Phys. 30(10)
one feedback loop
ESTRO IMRT course 2016
Adaptive Radiotherapy
London April 7th, 2016
-28-
1 cm margin
around CTV
CT
…
CT
deformable registration,
dose warping,
dose accumulation
model motion of each voxel, this
enables calculation of average
‘expected’ dose-per-voxel
probabilistic
IMRT
plan
new plan
optimizes the expected
dose-per-voxel