2776-2777 / 2953
This was all offline ART…
Now: Online Adaptive Re-Planning
IMRT
plan
CT
Fx
1
no margin!
IMRT
plan
CT
Fx
2
IMRT
plan
CT
Fx
N
…
Results (in short):
• average dose escalation by 13% possible, but with large interpatient
Ghilezan et al. 2004
(IJROBP 60(5))
ESTRO IMRT course 2016
Adaptive Radiotherapy
London April 7th, 2016
-33-
variation (5-41%).
• 27% of the patient would have only minimal benefit (<5% dose
escalation), 32% would have significant benefit (>15% dose esc.)
Note!:
•
comparison relative to non adaptive standard IMRT (1 cm margin),
not to offline adaptive IMRT.
•
no margin, intrafraction motion and all other uncertainties neglected