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Conclusions

offline adaptive

setup correction and margin adapting protocols with

clinically proven benefits and high efficiency to reduce systematic errors

online adaptive

schemes can further reduce uncertainties for the price

of more frequent imaging, but there is a lower limit for margin reduction

ESTRO IMRT course 2016

Adaptive Radiotherapy

London April 7th, 2016

-47-

provocative thought:

a single adaptation – if well implemented and its effects

evaluated thoroughly – is better than some ‘latest’ complex IGRT/ART scheme

with daily imaging and repeat adaptations

– unless its benefits are clearly proven with treatment simulation

approaches/patient data.