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Finally: Some (more) words of caution

Deformable registration errors => dose warping errors!

Deformable registration is especially challenging for prostate/rectum

The ‘latest-and-greatest’ ART schemes use methods from the

‘toolbox’, that start to find its way into commercial products

and thus into clinical practice.

BUT be aware…

ESTRO IMRT course 2016

Adaptive Radiotherapy

London April 7th, 2016

-49-

Thus: Are hot/cold spots in an accumulated dose real? Should these be

actively compensated for?

Dose calculation on cone beam CT data: no high-precision dose

calculation possible, thus dose-of-the-day calculation is subject to

errors