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2. Does the method contain
system suitability tests or
controls as specified by the
SMPR? If not, please indicate
if there is a need for such
tests or controls and which
ones.
yes
3. Is there information
demonstrating that the
method system suitability
tests and controls as
specified in the SMPR worked
appropriately and as
expected? If no, please
specify.
yes
4. Based on the supporting
information, is the method
written clearly and concisely?
If no, please specify the
needed revisions.
yes - this method is well written
5. Based on the supporting
information, what are the
pros/strengths of the
method?
This method appears to be rugged and performed well during the SLV study.
6. Based on the supporting
information, what are the
cons/weaknesses of the
method?
This method uses post column dervitization with Ninhydrin which requires some unique
instrumentation which may not be available in labs that are not familiar with amino acid
analysis.
7. Any general comments
about the method?
no
Do you recommend this
method be adopted as a First
Action and published in the
Official Methods of Analysis
of AOAC INTERNATIONAL?
Please specify rationale.
I recommend that this method be considered for AOAC Official First Action status for
the analysis of Theanine.