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INFORMS Nashville – 2016

291

5 - Optimizing Procurement Of High-value Medical Products In

A Health-care Network

Parimal Kulkarni, Manager, Supply Chain Analytics, BJC

Healthcare, 8300 Eager Rd, Suite 500 D Mailstop 92-92-277,

St Louis, MO, 63144, United States,

pskf44@umsl.edu

Parimal Kulkarni, Manager, Supply Chain Analytics, University of

Missouri, St.Louis, One University Blvd, St Louis, MO, 63121,

United States,

pskf44@umsl.edu,

L. Douglas Smith, Glen Moser

We use MILP optimization and simulation in concert to develop procurement

strategies for high-value medical supplies in a health-care network. With a multi-

objective MILP model, we determine product groups to be purchased from

alternative vendors to achieve quantity discounts while maintaining diversity of

supply. Considered are physician preference, budgetary limits, and scorecards of

vendor performance on several dimensions. Discrete-event simulation is used

iteratively to test procurement solutions and help set the MILP constraints to keep

risk at acceptable levels.

TB79

Legends G- Omni

Opt, Stochastic II

Contributed Session

Chair: Hernan Andres Caceres Venegas, Ph.D. Student, University at

Buffalo - SUNY, 342 Bell Hall, University at Buffalo, Buffalo, NY, 14260,

United States,

hernanan@buffalo.edu

1 - Efficient Solving Of Multi-stage Mixed-integer Stochastic

Problems Under Mean-dispersion Distributional Information

Krzysztof Postek, PhD Candidate, Tilburg University, Warandelaan

2, Tilburg, 5037 AB, Netherlands,

k.postek@tilburguniversity.edu

,

Ward Romeijnders, Dick den Hertog, Maarten H van der Vlerk

We propose a solution method for multi-stage robust optimization and stochastic

programming problems under distributional uncertainty, when the means and

mean absolute deviations of the parameters are known. Using new theoretical

results we show for problems with integer recourse how to construct good convex

approximations with known performance bounds and how to solve these

problems efficiently. Our approach gives insights into the performance of the

various recourse rules, the value of distributional information, and the trade-offs

between different variants of the objective function (worst-case, worst-case

expected, best-case).

2 - Multi-project Scheduling With Multi-mode Resource Constrained

Under Uncertainty

Berna Dengiz, Professor, Baskent University, Eskisehir Road

20th Km, Baglica Campus, Ankara, 06530, Turkey,

bdengiz@baskent.edu.tr,

Serdar Soysal

In this study, we address a resource constrained project scheduling problem

including uncertainties in resource usage rate in a multi-project environment.

The activities of each project have alternative resource usage modes. Resources

are dedicated to all projects considering their dedication policy. The projects

involve finish to start zero time lag, nonpreemptive activities and limited

renewable and nonrenewable resources. In this study, the optimal dedication of

resource capacities to the projects and minimum value of weighted tardiness over

all projects will be determined by proposed solution approach.

3 - Stochastic Integer Programming With Endogenous Uncertainty In

Open Access Outpatient Clinic Appointments Scheduling

Amarnath Banerjee, Associate Professor, Texas A&M University,

4041 Engineering Technology Building, 3131 Tamu, College

Station, TX, 77843-3131, United States,

banerjee@tamu.edu

,

Yu Fu

This study develops a two-stage Stochastic Integer Programming (SIP) model to

solve the online outpatient scheduling problem. The model considers different

types of patients and uncertain factors in system throughput, no-show,

cancellation and lateness. A modified L-shaped algorithm is designed to handle

the endogenous uncertainty brought by these factors and solve the SIP model.

The analysis method and solution algorithm can be applied to two-stage SIP

model with simple recourse function satisfying certain properties.

4 - A Stochastic Mixed Integer Programming Model For

Risk Minimization

Yiming Yao, Lawrence Livermore National Laboratory, 7000 East

Avenue, L-181, Livermore, CA, 94550-9234, United States,

yao3@llnl.gov

, Vic Castillo, Andrew Mastin, Carol A Meyers,

Deepak Rajan

We present a two-stage stochastic mixed integer programming model that

minimizes enterprise risk subject to supply, demand, capacity and other

constraints, with the consideration of uncertainty in some parameter values. We

describe risk measurement and uncertainty characterization in the application

context. Finally, we describe the model’s implementation in the open source

optimization modeling language PYOMO/PYSP.

5 - Pricing Tax Return For Students That Opt-out From Using

School Bus

Hernan Andres Caceres Venegas, PhD Student, University at

Buffalo - SUNY, 342 Bell Hall, University at Buffalo, Buffalo, NY,

14260, United States,

hernanan@buffalo.edu

, Rajan Batta,

Qing He

School districts are often mandated to provide transportation but can encounter

ridership that varies between 22-72 percent. Consequently, buses run with

unused capacity over long routes. We explore the scenario where students are

compensated for giving up the option to ride a bus, in an effort to reduce the

overall cost of the system. Mathematical formulations for this problem are

developed and analyzed. Results from a case study along with algorithmic

computational results will be presented.

TB86

GIbson Board Room-Omni

Monte Carlo Methods for Multi-stage Decision

Making under Uncertainty

Sponsored: Artificial Intelligence

Sponsored Session

Chair: Michael Fu, University of Maryland,

mfu@isr.umd.edu

1 - Back To The Future: Google Deep Mind, Alpha Go & Monte Carlo

Tree Search

Michael Fu, University of Maryland, College Park, MD, 20742,

United States,

mfu@rhsmith.umd.edu

In March 2016 in Seoul, Korea, Google DeepMind’s AlphaGo, a computer Go-

playing program, defeated the reigning human world champion Go player, a feat

far more impressive than previous computer programs victories in chess (Deep

Blue) and Jeopardy (Watson). Due to the sheer combinatorial nature of the

number of possibly game configurations, at the heart of all computer Go-playing

algorithms is Monte Carlo tree search based on an upper confidence bound (UCB)

algorithm that traces its roots back to an adaptive multi-stage sampling algorithm

for estimating the value function in finite-horizon Markov decision processes

(MDPs). We describe this algorithm and the main ideas behind AlphaGo.

2 - Cumulative Prospect Theory Meets Reinforcement Learning:

New Monte Carlo Algorithms

Cheng Jie, University of Maryland,

cjie@math.umd.edu,

Prashanth

L.A., Michael Fu, Marcus Steve, Csaba Szepesvari

We bring cumulative prospect theory (CPT) to a risk-sensitive reinforcement

learning (RL) setting and present Monte Carlo simulation-based algorithms for

both estimation and optimization. The estimation scheme uses the empirical

distribution to estimate the CPT-value of a random variable. The optimization

procedure is based on simultaneous perturbation stochastic approximation

(SPSA). Both theoretical convergence results and numerical experiments are

provided.

3 - Weighted Bandits Or: How Bandits Learn Distorted Values That

Are Not Expected

L. A. Prashanth, University of Maryland, College Park, MD, 20742,

United States,

prashla@umd.edu

, Aditya Gopalan, Michael Fu,

Steve Marcus

We formulate a novel multi-armed bandit setup, where the arms’ reward

distributions are distorted by a weight function. The distortions are motivated by

models of human decision making that have been proposed to explain commonly

observed deviations from conventional expected value preferences We study two

representative problems in this setup: The classic K-armed bandit setting and the

linearly parameterized bandit setting. In both settings, we propose algorithms that

are inspired by UCB, incorporate reward distortions and exhibit sub-linear regret

assuming Holder-continuous weights. We provide empirical demonstrations of the

advantage due to using distortion-aware learning algorithms.

TB86