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0

20

40

60

0

25

50

75

100

Control

10Gy + 3mg/kg R848 q1w

10Gy + 3mg/kg R848 q1w

+

CD8 mAb

***

Time after tumor

implantation (days)

Percent survival

0

20

40

60

0

25

50

75

100

Control

5x2Gy RT

3mg/kg R848 q1w + 5x2Gy RT

**

++

3mg/kg R848 q1w

Time after tumour

implantation (days)

Percent survival

0

20

40

60

0

25

50

75

100

NT

3 mg/kg R848 q1w

5x2Gy RT

5x2Gy RT + 3 mg/kg

R848 q1w

**

+

Time after tumor

implantation (days)

Percent survival

EG7 model of T cell Lymphoma

EL4 model of T cell Lymphoma

A20 model of B cell Lymphoma