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JD Brody,
J Clin Oncol 2010;28(28):4324-4332
In situ vaccination with a TLR9 agonist
induces systemic lymphoma response
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15 patients with r/r iNHL
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CpG + low-dose RT single site of disease
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Response assessment at distant sites
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Treatment induced CD8+ memory T cells and Treg expansion in some patients
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Best response in Tregs non inducers