Conclusions (1)
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Anti -PD-1-pathway-blocking agents highly active in HL but more limited
efficacy in other lymphomas. Mechanistic insights are emerging in HL
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Currently very large number of combination therapies involving anti-PD-
1/PD-L1 agents and conventional chemotherapies, targeted therapies, or
other immunotherapies are being studied
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CAR-T cells look promising in relapsed and refractory DLBCL and other
lymphoid malignancies. Efficacy and validity of delivery require on-going
further international studies
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Clinical trials outrunning new immunological scientific insights.