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Tumour A=irradiated, B=shielded
2 4 h r s
7 2 h r
7 d a y s
2 4 h r s
7 2 h r
7 d a y s
2 4 h r s
7 2 h r
7 d a y s
2 4 h r s
7 2 h r
7 d a y s
0
5
1 0
1 5
2 0
A
B
A
B
N o n T re a te d
5 x 2 G y R T
F re q u e n c y o f C D 1 1 b
+
G R 1
H i
/ C D 4 5
+
**
**
*
*
Local fractionated RT leads to increases in MDSC only in RT field
Dovedi et Clin Cancer Res 2017