2 4 h r s
7 2 h r
7 d a y s
2 4 h r s
7 2 h r
7 d a y s
2 4 h r s
7 2 h r
7 d a y s
2 4 h r s
7 2 h r
7 d a y s
0
5 0 0 0
1 0 0 0 0
1 5 0 0 0
2 0 0 0 0
2 5 0 0 0
A
B
A
B
N o n T re a te d
5 x 2 G y R T +
P D -1 m A b
*
**
P D -L 1 e x p re s s io n o n
C D 4 5 - tu m o u r c e lls
*
*
*
**
Does RT and anti-PD1 leads to generation of systemic anti-tumour
immune responses ?
Dovedi et Clin Cancer Res 2017