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HD11: Second neoplasias
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No difference in the SIR: A= 1.4, B= 2.4, C= 2.2, D= 1.7
compared to the age- and sex-specific incidence in the German general population
356
285
113
14
347
281
99
12
341
273
124
16
351
279
124
16
Pts. at risk
0 12 24 36 48 60 72 84 96 108 120 132 144 156 168 180
Time [months]
0.0
0.1
0.2
0.3
Cumulative incidence +/- 95%-CI
BEACOPP+20Gy
BEACOPP+30Gy
ABVD+20Gy
ABVD+30Gy
10-year estimate [95%-CI]
ABVD+30Gy 5.8% [2.7% to 9.0%]
ABVD+20Gy 6.5% [3.7% to 9.3%]
Bbas+30Gy 6.7% [3.7% to 9.7%]
Bbas+20Gy 5.4% [2.5% to 8.3%]
Median observation time 106 months
Bröckelmann et al; EHA 2016