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175

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

W

E

D

N

E

S

D

A

Y

3073-P

os

B

oard

B503

CARDIOPROTECTIVE ROLES OF NEURONAL CA

2+

SENSOR-1

DURING STRESS.

Tomoe Y. Nakamura-Nishitani

, Shu Nakao, Shigeo

Wakabayashi

3074-P

os

B

oard

B504

INITIATION OF ELECTRON TRANSPORT ACTIVITY AND A

DECREASE OF OXIDATIVE STRESS OCCUR SIMULTANEOUSLY

DURING EMBRYONIC HEART DEVELOPMENT. Gisela Beutner,

George A. Porter, Jr.

3075-P

os

B

oard

B505

cpow

travel awardee

THE STOICHIOMETRY BETWEEN MICU1 AND MCU

DETERMINES THE DIFFERENT MITOCHONDRIAL CA

2+

UPTAKE PHENOTYPES IN HEART AND LIVER.

Melanie Paillard

,

György Csordás, Tünde Golenár, Cynthia Moffat, Erin Seifert, György

Hajnóczky

3076-P

os

B

oard

B506

ER CALCIUM RELEASE IS TUNED BY MITOCHONDRIAL

REDOX NANODOMAINS.

David M. Booth

, Balázs Enyedi, Miklós

Geiszt, Péter Várnai, György Hajnóczky

3077-P

os

B

oard

B507

REACTIVE OXYGEN SPECIES (ROS) SUPPRESS

MITOCHONDRIAL MOTILITY.

Valentina Debattisti

, Masao

Saotome, Sudipto Das, Gyorgy Hajnoczky

3078-P

os

B

oard

B508

MIRO1 IS DISPENSABLE FOR CALCIUM-MEDIATED

INHIBITION OF MITOCHONDRIAL MOVEMENT.

David B. Weaver

, Agnieszka Lewandowska, Tammy T. Nguyen, Valentina

Debattisti, Janet M. Shaw, Gyorgy Hajnoczky

3079-P

os

B

oard

B509

MITOCHONDRIAL FUSION DYNAMICS IN THE

HEART.

Veronica Eisner

, Ryan Cupo, Erhe Gao, György Csordás, Lan

Cheng, Jessica Ibetti, J. Kurt Chuprun, Walter J. Koch, György Hajnóczky

3080-P

os

B

oard

B510

MECHANISTIC CHARACTERIZATION OF THE THIOREDOXIN

SYSTEM IN THE REMOVAL OF HYDROGEN PEROXIDE.

Venkat R. Pannala

, Ranjan K. Dash

3081-P

os

B

oard

B511

HIGHER MITOCHONDRIAL MEMBRANE POTENTIAL

INDUCES ROS PRODUCTION IN THE FAMILIAR FORM

OF FRONTOTEMPORAL DEMENTIA WITH MAPT

MUTATIONS.

Noemi Esteras Gallego

, Selina Wray, Elisavet Preza,

Andrey Y. Abramov

3082-P

os

B

oard

B512

international

travel awardee

THE OVEREXPRESSION OF SUPEROXIDE DISMUTASE

1 RESTORES GROWTH DEFECT IN A PORIN1-LESS

YEAST STRAIN AND IMPROVES MITOCHONDRIAL

METABOLISM.

Andrea Magrì

, Simona Reina, Flora M. Tomasello,

Maria C. Di Rosa, Angela Messina, Vito De Pinto

3083-P

os

B

oard

B513

THE ROLE OF COMPLEX I IN MITOCHONDRIAL REACTIVE

OXYGEN SPECIES FORMATION IN COCHLEAR SENSORY AND

SUPPORTING CELLS DURING OTOTOXIC AMINOGLYCOSIDE

EXPOSURE.

Danielle Desa

, Michael G. Nichols, Heather Jensen Smith

3084-P

os

B

oard

B514

MITOCHONDRIAL IRON AND SPHINGOSINE SYNERGIZE

INITIATION OF HEPATOCYTE DEATH BY AUGMENTING

OXIDATIVE STRESS.

Sergei A. Novgorodov

, Tatyana I. Gudz, Andaleb

Kholmukhamedov, Raymond Deepe, John J. Lemasters

Cellular Signaling and Metabolic

Networks (Boards B515-B530)

3085-P

os

B

oard

B515

GUARDIAN FUNCTION OF MITSUGUMIN 53 IN CELL

MEMBRANE REPAIR AND METABOLIC SYNDROME.

Hanley Ma

,

Jason Liu, Zehua Bian, Yuqi Cui, Xinyu Zhou, Xuefeng Zhou, Bo Zhang,

Timothy M. Adesanya, Ki Ho Park, Hua Zhu

3086-P

os

B

oard

B516

NON-INVASIVE INTEROGATION OF SIGNALING ACTIVATED

GENE REGULATION.

Gregor Neuert

3087-P

os

B

oard

B517

MONTE CARLO SIMULATION OF WNT PROPAGATION BY

A NOVEL TRANSPORT MECHANISM COMPLEMENTING A

JOINT EXPERIMENTAL STUDY.

Claude Sinner

, Eliana Stanganello,

Anja I.H. Hagemann, Benjamin Mattes, Dana Meyen, Sabrina Weber,

Erez Raz, Steffen Scholpp, Alexander Schug

3088-P

os

B

oard

B518

A GENETICALLY-ENCODED FRET SENSOR BASED ON AMP-

ACTIVATED PROTEIN KINASE REPORTS ALLOSTERIC KINASE

ACTIVATION.

Uwe Schlattner

, Martin Pelosse, Imre Berger

3089-P

os

B

oard

B519

INTEGRATED OMIC ANALYSIS OF A GUINEA PIG MODEL OF

HEART FAILURE AND SUDDEN CARDIAC DEATH.

D. Brian Foster

, Ting Liu, Robert N. O’Meallly, C. Conover Talbot Jr.,

Robert N. Cole, Brian O’Rourke

3090-P

os

B

oard

B520

CELLULAR SIGNALING NETWORKS FUNCTION AS

GENERALIZED WIENER-KOLMOGOROV FILTERS TO

SUPPRESS NOISE.

Michael Hinczewski

, Devarajan Thirumalai

3091-P

os

B

oard

B521

TO GROW IS NOT ENOUGH: THE IMPACT OF CELL RESPONSE

TIME ON FITNESS.

Nash Rochman

, Fangwei Si, Sean Sun

3092-P

os

B

oard

B522

BCL-2 OVEREXPRESSION STIMULATES GLYCOLYSIS

AND LACTIC FERMENTATION IN A BAX-DEPENDENT

FASHION. Bushra Mahmood, Jessica Wilson, Miriam Ahmad, Patricia

Olino, Justin King,

Laurent Dejean

3093-P

os

B

oard

B523

HUMAN ADIPOSE CELL RESPONSE TO INSULIN: ANALYSIS

OF CELLULAR SWITCH-LIKE TRANSFORMATIONS AND

DISTRIBUTIONS. Vladimir A. Lizunov,

Paul S. Blank

, Karin G.

Stenkula, Monica Skarulis, Samuel Cushman, Joshua Zimmerberg

3094-P

os

B

oard

B524

ACCELERATING SYSTEMS BIOLOGY COMPUTATION:

ENHANCED SAMPLING OF SPATIALLY REALISTIC

STOCHASTIC MODELS USING THE WEIGHTED ENSEMBLE

APPROACH.

Rory Donovan

3095-P

os

B

oard

B525

ACCUMULATIONS AND ENERGY RECYCLING PATHWAY

IN P. FALCIPARUM GAMETOCYTE-INFECTED HUMAN

ERYTHROCYTES.

Fuyuki Tokumasu

, Takeshi Q. Tanaka, Suzumi

Tokuoka, Daichi Nakatani, Shin-ichiro Kawazu, Kiyoshi Kita

3096-P

os

B

oard

B526

PHOTO-REGULATION OF THE INTERACTION BETWEEN

RAS AND RALGDS USING GTP ANALOGUES COMPOSED OF

PHOTOCHROMIC MOLECULES. Kaori Masuhara, Seigo Iwata,

Nobuhisa Umeki,

Shinsaku Maruta