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171

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

W

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2981-P

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B411

PASSIVE FORCE ANALYSIS OF SINGLE SARCOMERES FROM

MUSCLES LACKING ARGINYL-TRNA-PROTEIN TRANSFERASE

(ATE1).

Felipe de Souza Leite

, Fabio C. Minozzo, Neal Trecarten,

Xuemei Han, John R. Yates, Anna Kashina, Dilson E. Rassier

2982-P

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B412

DIRECT EVIDENCE FOR THE EFFECT OF TITIN STIFFNESS

ON THICK-FILAMENT MECHANICAL PROPERTIES IN

STRETCHED MUSCLE SARCOMERES. Yong Li,

Wolfgang A. Linke

2983-P

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B413

RESIDUAL FORCE ENHANCEMENT IN CARDIAC

MYOFIBRILS.

Kevin R. Boldt

, Venus Joumaa, Walter Herzog

2984-P

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B

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B414

THE EFFECTS OF TITIN DEGRADATION ON PASSIVE

STIFFNESS PROPERTIES OF SKINNED RABBIT PSOAS FIBERS

DURING OSMOTIC COMPRESSION.

Ian C. Smith

, Walter Herzog

2985-P

os

B

oard

B415

ELEVATED IONIC STRENGTH DIMINISHES FORCE/CROSS-

BRIDGE AND THE NUMBER OF FORCE-GENERATING CROSS-

BRIDGES. Li Wang, Anzel Bahadir,

Masataka Kawai

2986-P

os

B

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B416

FORMATION OF THE MOTOR PROTEIN-PHOTOCHROMIC

ADP ANALOGUE-FLUOROMETAL TERNARY COMPLEX AND

PHOTO-REVERSIBLE TRANSITION ALONG THE STEPS IN

ATPASE CYCLE.

Akihisa Iwata

, Takeshi Itaba, Mitsuo Ohmori, Shinya

Mitsuhashi, Shinsaku Maruta

2987-P

os

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B417

BACKBONE ORIENTATION AND DISTANCE MEASUREMENTS

IN MYOSIN II: APPLICATIONS OF HIGH-RESOLUTION EPR

USING A BIFUNCTIONAL SPIN LABEL.

Benjamin P. Binder

,

Andrew R. Thompson, Sinziana Cornea, Rebecca J. Moen, David D.

Thomas

2988-P

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B

oard

B418

POST-TRANSLATIONAL MODIFICATION OF TUBULIN

AMPLIFIES X-ROS SIGNALING IN STRIATED MUSCLE.

Jaclyn P. Kerr

, Benjamin L. Prosser, Guoli Shi, Patrick Robison, Aaron

M. Kempema, Joseph K. Hexum, Daniel A. Harki, Stuart S. Martin,

Roberto Raiteri, Christopher W. Ward

2989-P

os

B

oard

B419

RELOADING INJURY, CHRONIC RECOVERY, AND FIBER TYPE

ADAPTION OF MOUSE SOLEUS MUSCLE AFTER FOUR WEEKS

OF HIND LIMB SUSPENSION.

Hanzhong Feng

, Moh H. Malek,

Xue-Qun Chen, Jian-Ping Jin

2990-P

os

B

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B420

MINIMUM AND MAXIMUM LIMIT TO NUMBER OF

MYOSIN II MOTORS PARTICIPATING IN AN ENSEMBLE

MOTILITY.

Khushboo Rastogi

, Shabeel Hamnaf, Vikas Pandey, Sunil

Nath, Ravikrishnan Elangovan

2991-P

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B421

MUSCLE SHORTENING VELOCITY IS MODULATED BY

ALTERNATIVE MYOSIN CONVERTERS.

Christopher S. Newhard

,

Bernadette M. Glasheen, Debra Sheppard, Lauren Riley, Douglas M.

Swank

2992-P

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oard

B422

ACTOMYOSIN REGULATION BY CONSERVED SITES OF

TM5NM1 (TPM3.1), A NONMUSCLE TROPOMYOSIN.

Bipasha Barua

, Sarah E. Hitchcock-DeGregori

2993-P

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B423

THE BINDING OF S1A1-ADP TO SKELETAL THIN FILAMENTS

IS INSENSITIVE TO THE PRESENCE OF COVALENTLY BOUND

PHOSPHATE IN TROPOMYOSIN.

David H. Heeley

, Charitha L.

Goonasekara, White D. Howard

2994-P

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B424

THE FUNCTIONAL CONSEQUENCES OF HYPERTROPHIC

CARDIOMYOPATHY TROPONIN C MUTATIONS IN THE

REGULATION OF SLOW SKELETAL MUSCLE CONTRACTION:

THE PROTECTIVE ROLE OF SLOW SKELETAL TROPONIN

I. Tiago Veltri, Clara A. Michell, Maicon Landim, David Dweck,

Jose R. Pinto

2995-P

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B425

STRUCTURAL AND FUNCTIONAL CHANGES IN SKELETAL

MUSCLES IN AN A8V-TROPONIN C HYPERTROPHIC

CARDIOMYOPATHY KNOCK-IN MOUSE MODEL. Milica

Vukmirovic, Marcos Angel Sanchez-Gonzalez, Gregory S. Frye, Andrew

Koutnik,

David A. Gonzalez

, Edda Ruiz, Eric Krivensky, David Dweck,

Leonardo F. Ferreira, Jose Renato Pinto

2996-P

os

B

oard

B426

MODELLING THE CALCIUM DEPENDENT ACTIN-MYOSIN

ATP-ASE CYCLE IN SOLUTION. Srboljub M. Mijailovich, Djordje

Nedic, Marina Svicevic, Boban Stojanovic,

Michael Geeves

2997-P

os

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B427

EFFECT OF ACTIN AND NUCLEOTIDE ON THE MOVEMENT

OF A1-TYPE MYOSIN ESSENTIAL LIGHT CHAIN, DETECTED

BY TIME-RESOLVED FRET.

Piyali Guhathakurta

, Ewa Prochniewicz,

David D. Thomas

2998-P

os

B

oard

B428

SYSTEMATIC VARIATIONS IN FAST-TYPE MYOSIN LIGHT

CHAIN 1 SEQUENCE CORRELATE WITH SPECIES BODY

MASS.

Peter J. Reiser

, Sabahattin Bicer

Cardiac Muscle Regulation II (Boards

B429-B444)

2999-P

os

B

oard

B429

CARDIAC OVER-EXPRESSION OF CREATINE KINASE

IMPROVES FUNCTION IN FAILING MYOCYTES.

Carlo G. Tocchetti

, Michelle Leppo, Yibin Wang, Robert G. Weiss,

Nazareno Paolocci

3000-P

os

B

oard

B430

ACUTE ABLATION OF CARDIAC MYOSIN LIGHT CHAIN

KINASE DECREASES CARDIAC PERFORMANCE.

Audrey N. Chang

, Pavan Battiprolu, Joseph A. Hill, Kristine E. Kamm,

James T. Stull

3001-P

os

B

oard

B431

CARDIAC REMODELING IN THE MOUSE MODEL OF MARFAN

SYNDROME DEVELOPS INDEPENDENTLY FROM AORTIC AND

VALVULAR ABNORMALITIES.

Natalia Petrashevskaya

, Hyun-Jin

Tae, Shanon Marshall, Melissa Krawczyk, Mark Talan

3002-P

os

B

oard

B432

TRANSGENIC OVER-EXPRESSION OF CARBONIC ANHYDRASE

III IN CARDIAC MUSCLE DEMONSTRATES A MECHANISM TO

RESIST ACIDOSIS.

Hanzhong Feng

, Jian-Ping Jin