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172

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

3003-P

os

B

oard

B433

MYOCARDIAL INTERSTITIAL SEROTONIN AND ITS MAJOR

METABOLITE, 5-HYDROXYINDOLE ACETIC ACID LEVELS

DETERMINED BY MICRODIALYSIS TECHNIQUE IN IN VIVO

RAT HEART.

Cheng-Kun Du

, Dong-Yun Zhan, Tsuyoshi Akiyama,

Takashi Sonobe, Tadakatsu Inagaki, Mikiyasu Shirai

3004-P

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B434

THE TREATMENT BENEFIT OF GHRELIN ON A MOUSE

MODEL OF INHERITED DILATED CARDIOMYOPATHY

CAUSED BY TROPONIN MUTATION.

DongYun Zhan

, ChengKun

Du, Sachio Morimoto, Tsuyoshi Akiyama, Daryl O Schwenke, Hiroshi

Hosoda, Kenji Kangawa, Mikiyasu Shirai

3005-P

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B435

THE CARDIAC TROPONIN T MUTANT MISSING THE

N-TERMINAL EXTENSION CAUSES DOSE-DEPENDENT

EFFECTS ON CARDIAC FUNCTION AND REMODELING IN

TRANSGENIC MICE. Sampath K. Gollapudi, Joseph Maricelli,

John J. Michael

, O. Lynne Nelson, Dan B. Rodgers, Murali Chandra

3006-P

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B436

education

travel awardee

FUNCTIONAL EFFECTS OF THE H1-HELIX OF RAT CARDIAC

TROPONIN T ON CROSSBRIDGE DETACHMENT RATE IS

DIFFERENTLY MODULATED BY

α

- AND

β

-MYOSIN HEAVY

CHAIN ISOFORMS.

John J. Michael

, Murali Chandra

3007-P

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B437

ENGINEERING CARDIAC TROPONIN C: POTENTIAL

THERAPEUTIC FOR HEART FAILURE.

Vikram Shettigar

, Sean C.

Little, Bo Zhang, Jianchao Zhang, Steve Roof, Zhaobin Xu, Elizabeth A.

Brundage, Brandon J. Biesiadecki, Noah Weisleder, Paul Janssen, Mark T.

Ziolo, Jonathan P. Davis

3008-P

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B438

MODELING THE RESPONSE OF CARDIAC TROPONIN C TO

CALCIUM ON THE THIN FILAMENT: EFFECTS OF DISEASE-

RELATED AND POST-TRANSLATIONAL MODIFICATIONS.

Jalal K. Siddiqui

, Bin Liu, Shane D. Walton, Vikram K. Shettigar,

Andrew J. O’Neil, Grace A. Davis, Peeyush Shrivastava, Jonathan P. Davis

3009-P

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B439

THE CONTRIBUTION OF MYOSIN BINDING PROTEIN-C AND

TROPONIN I PHOSPHORYLATION TO THE

β

-ADRENERGIC

ACCELERATION OF LEFT VENTRICULAR CONTRACTION

AND RELAXATION.

Kenneth S. Gresham

, Julian E. Stelzer

3010-P

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B440

MOLECULE SPECIFIC EFFECTS OF PKA-MEDIATED

PHOSPHORYLATION ON MYOFIBRILLAR FUNCTION.

Laurin M. Hanft

, Brandon J. Biesiadecki, Craig A. Emter, Kerry S.

McDonald

3011-P

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B441

LENGTH-DEPENDENT CONTRACTILE DYNAMICS ARE

BLUNTED UPON ABLATION OF CARDIAC MYOSIN BINDING

PROTEIN-C.

Ranganath Mamidi

, Kenneth S. Gresham, Julian E.

Stelzer

3012-P

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B442

CARDIAC TROPONIN I SER-23/24 AND TYR-26

PHOSPHORYLATION CROSSTALK.

Hussam E. Salhi

, Shane D.

Walton, Nathan C. Hassel, Elizabeth A. Brundage, Pieter P. de Tombe,

Paul M.L. Janssen, Jonathan P. Davis, Brandon J. Biesiadecki

3013-P

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B443

CARDIAC MYOSIN ESSENTIAL LIGHT CHAIN N-TERMINUS

REGULATES MOTOR STEP-SIZE. Yihua Wang, Katalin Ajtai,

Katarzyna Kazmierczak, Danuta Szczesna-Cordary,

Thomas P. Burghardt

3014-P

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B444

HUMAN IPS CELL-DERIVED CARDIOMYOCYTES CARRYING

MHC-R403Q EXHIBIT ASPECTS OF HYPERTROPHIC

CARDIOMYOPATHY IN VITRO.

Eugenia Jones

, Coby B. Carlson,

Chad Koonce, Natsuyo Aoyama, Jun Wang, Benjamin Meline, Steven J.

Kattman, Blake Anson

Cytoskeletal-based Intracellular Transport

(Boards B445-B449)

3015-P

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B445

CONTROL OF THE INITIATION AND TERMINATION OF

KINESIN-1-DRIVEN TRANSPORT BY MYOSIN-IC AND NON-

MUSCLE TROPOMYOSIN.

Betsy B. McIntosh

, Erika L.F. Holzbaur,

E. Michael Ostap

3016-P

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B446

VISUALIZING MELANOSOME TRANSFER IN VIVO.

John A. Hammer

, Xufeng S. Wu

3017-P

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B447

THE EFFECTS OF WILD-TYPE AND DISEASE-LINKED TAU

MUTANTS ON CARGO TRANSPORT IN CELLS. Dezhi Yu, Stuart

Feinstein,

Megan T. Valentine

3018-P

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B448

ENVIRONMENTAL INFLUENCE ON MICROTUBULE-BASED

BIDIRECTIONAL CARGO TRANSPORT.

Sarah Klein

, Cecile Appert-

Rolland, Ludger Santen

3019-P

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B449

A SINGLE-MOLECULE VIEW ON KINESIN MOTOR-PROTEIN

COOPERATION IN INTRAFLAGELLAR TRANSPORT IN LIVING

C. ELEGANS. Bram Prevo, Pierre J.J. Mangeol, Felix Oswald, Jonathan

M. Scholey,

Erwin J.G. Peterman

Bacterial Mechanics, Cytoskeleton, and

Motility (Boards B450-B467)

3020-P

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B450

COLONIZATION, COMPETITION, AND DISPERSAL OF

PATHOGENS IN FLUID FLOW NETWORKS.

MinYoung Kevin

Kim

, Albert Siryaporn, Yi Shen, Zemer Gitai, Howard A. Stone

3021-P

os

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B451

SPATIAL REGULATORS FOR BACTERIAL CELL DIVISION

SELF-ORGANIZE INTO AN OSCILLATOR ON A FLAT

BILAYER.

Anthony Vecchiarelli

, Ling Chin Hwang, Min Li, Yeonee

Seol, Michiyo Mizuuchi, Keir Neuman, Kiyoshi Mizuuchi

3022-P

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B452

POSITIVE REGULATION MECHANISM IN LOCALIZING CELL

DIVISION PROTEINS IN ESCHERICHIA COLI. Matthew W. Bailey,

Jaan Männik

3023-P

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B453

CELL DIVISION REGULATORS MINC AND MIND FORM

POLYMERS IN THE PRESENCE OF NUCLEOTIDE.

Joseph Conti

,

Marissa Viola, Jodi Camberg

3024-P

os

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B454

SUPERRESOLUTION INVESTIGATION OF THE E. COLI CELL

DIVISION RING DURING CONSTRICTION.

Carla Coltharp

, Jie

Xiao