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169
Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
W
E
D
N
E
S
D
A
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2935-P
os
B
oard
B365
A PQ-CHANNEL MUTATION ASSOCIATED WITH EPILEPSY
ALTERS THE VOLTAGE DEPENDENCE OF CHANNEL
INACTIVATION. Ellie Dubrovina, Gabrielle Suppa, Keith Thomas,
Zafir Buraei
2936-P
os
B
oard
B366
cpow
travel awardee
β
2A AND
β
3 DIFFERENTIALLY MODULATE TIME- AND
VOLTAGE-DEPENDENT PROPERTIES OF INDIVIDUAL
VOLTAGE SENSORS IN THE HUMAN CAV1.2
CHANNEL.
Nicoletta Savalli
, Daniel Sigg, Alan Neely, Riccardo Olcese
2937-P
os
B
oard
B367
THE
α
2
δ
SUBUNIT EFFICIENTLY COUPLES VSDS ACTIVATION
TO PORE OPENING IN HUMAN CAV1.2 CHANNELS.
Nicoletta
Savalli
, Antonios Pantazis, Daniel Sigg, Alan Neely, Riccardo Olcese
2938-P
os
B
oard
B368
cpow
travel awardee
GENETIC ABLATION OF KLHL1 ALTERS CAV3.2
EXPRESSION IN DRG NEURONS AND MECHANICAL PAIN
TRANSMISSION.
Elizabeth Martinez-Hernandez
, Yungui He, Paula P.
Perissinotti, Erik Almazan, Michael D. Koobb, Erika S. Piedras-Renteria
2939-P
os
B
oard
B369
MORPHOLINO OLIGOMER PEPTIDE THERAPY
IMPROVES MITOCHONDRIAL FUNCTION IN
MDX
CARDIOMYOPATHY. Victoria P. Johnstone, Abbie M. Adams, Steve D.
Wilton, Sue Fletcher,
Livia C. Hool
2940-P
os
B
oard
B370
HIGH SUSCEPTIBILITY TO NON-ALCOHOLIC FATTY
LIVER DISEASE IN TWO-PORE CHANNEL 2-DEFICIENT
MICE. Christian Grimm, Cheng-Chang Chen, Elisabeth Butz, Martin
Biel,
Christian Wahl-Schott
Ion Channels, Pharmacology, and Disease
(Boards B371-B400)
2941-P
os
B
oard
B371
RELEVANCE OF SARS-COV E PROTEIN ION CHANNEL
ACTIVITY IN VIRUS PATHOGENESIS.
Carmina Verdiá Báguena
,
José L. Nieto-Torres, Marta L. De Diego, Jose M. Jimenez-Guardeño,
Jose A. Regla-Nava, Raul Fernandez-Delgado, carlos Castaño-Rodríguez,
Jaume Torres, Antonio Alcaraz, Vicente M. Aguilella, Luis Enjuanes
2942-P
os
B
oard
B372
DIVALENT COPPER COMPOUND AS INHIBITORY AGENT
OF INFLUENZA A.
Kelly L. McGuire
, Nathan A. Gordon, Roger G.
Harrison, David D. Busath
2943-P
os
B
oard
B373
INSIGHTS ON MOLECULAR DETERMINANTS OF
HERG K
+
CHANNEL INHIBITION: DESIGN, SYNTHESIS,
AND BIOLOGICAL EVALUATION OF LUBELUZOLE
DERIVATIVES.
Roberta Gualdani
, Maria Maddalena Cavalluzzi,
Francesco Tadini-Buoninsegni, Maria Rosa Moncelli, Giovanni Lentini
2944-P
os
B
oard
B374
VALIDATION OF KCA3.1 CHANNEL NIFEDIPINE
INTERACTION SITE PREDICTED BY ROSETTA MODELING
METHOD.
Hai M. Nguyen
, Heike Wulff, Vladimir Yarov-Yarovoy
2945-P
os
B
oard
B375
GBR-12909: POTENT BLOCKER OF PEAK AND LATE NAV1.5
CURRENTS.
Carlos Obejero-Paz
, James Kramer, Andrew Bruening-
Wright, Antonio Lacerda, Arthur Brown
2946-P
os
B
oard
B376
VX-770 AND NPPB MODULATE CFTR GATING VIA DIFFERENT
BUT DEPENDENT MECHANISMS.
Wen Ying Lin
, Kangyang Jih,
Tzyh-chang Hwang
2947-P
os
B
oard
B377
“USE DEPENDENCE” WITHOUT A BALL AND CHAIN
- INHIBITION OF BACTERIAL SODIUM CHANNELS BY
μ-CONTOXINS. Rocio K. Finol-Urdaneta, Denys McMaster,
Robert J. French
2948-P
os
B
oard
B378
W493R GAIN OF FUNCTION MUTATION IN ATYPICAL CYSTIC
FIBROSIS REWIRES THE EPITHELIAL SODIUM CHANNEL
DYNAMICS.
Mahmoud Shobair
, Yan H. Dang, Hong He, Jack M.
Stutts, Nikolay V. Dokholyan
2949-P
os
B
oard
B379
ROLE OF THREONINE 338 IN CFTR GATING.
Hsuan-Ting Kuo
,
Tzyh-Chang Hwang
2950-P
os
B
oard
B380
PP1 ANCHORING ONTO NCX1 FACILITATES
DEPHOSPHORYLATION OF P-SER68-PLM.
Tandekile Lubelwana
Hafver
, Pimthanya Wanichawan, Kjetil Hodne, Jan Magnus Aronsen,
Bjørn Dalhus, Marianne Lunde, Ulla Enger, Marita Mathisen, William
Fuller, Ivar Sjaastad, Ole Sejersted, Cathrine Carlson
2951-P
os
B
oard
B381
THE PORE-DOMAIN OF TRPA1 MEDIATES THE
INHIBITORY EFFECT OF THE ANTAGONIST 6-METHYL-5-(2-
(TRIFLUOROMETHYL)PHENYL)-1H-INDAZOLE.
Hans Moldenhauer
, Ramon Latorre, Jorg Grandl
2952-P
os
B
oard
B382
PLANAR PATCH CLAMP SYSTEM CAPABLE OF RECORDING
MECHANOSENSITIVE ACTIVITY OF ION CHANNELS.
Ken Takahashi
, Keiji Naruse
2953-P
os
B
oard
B383
SINGLE-CHANNEL ANALYSIS OF THE MOLECULAR
PHARMACOLOGY OF THE LONG QT SYNDROME VARIANT 3.
Seth H. Robey
, Kevin J. Sampson, Robert S. Kass
2954-P
os
B
oard
B384
AUTOMATED PATCH-CLAMP PHARMACOLOGY ASSAYS USING
HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED
CARDIOMYOCYTES. Olaf Scheel, Stefanie Frech,
Bogdan P. Amuzescu
, Jörg Eisfeld, Kun-Han Lin, Thomas Knott
2955-P
os
B
oard
B385
PHARMACOLOGICAL CHARACTERIZATION OF NR1/
NR2A AND NR1/NR2B GLUTAMATE RECEPTORS USING AN
ELECTROPHYSIOLOGY BASED HTS ASSAY.
Nikolai Fedorov
, Yuri
Kuryshev, Amy Wright, Zhiqi Liu, Luke Armstrong, Glenn E. Kirsch,
Arthur M. Brown
2956-P
os
B
oard
B386
CHARACTERIZATION OF SMALL MOLECULE MODULATORS
OF THE CYSTIC FIBROSIS TRANSMEMBRANE
CONDUCTANCE REGULATOR USING BACKSCATTERING
INTERFEROMETRY.
Ashley Lockwood
, David Heidary, Christopher
Richards, Michael Baksh, M.G. Finn
2957-P
os
B
oard
B387
DANTROLENE INHIBITION OF RYR2 REQUIRES
CALMODULIN.
Ye W. Oo
, N Gomez-Hurtado, D.F. vanHelden, M. S
Imtiaz, B.C Knollmann, D.R Laver