168
Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
2910-P
os
B
oard
B340
EXPRESSION, PURIFICATION, AND PRELIMINARY
CHARACTERIZATION OF A HUMAN CARDIAC SODIUM
CHANNEL VOLTAGE SENSING DOMAIN.
Mohammed H. Bhuiyan
, Sebastien F. Poget
2911-P
os
B
oard
B341
A THERMODYNAMIC ANALYSIS OF DISEASE-CAUSING
MUTATIONS IN THE NAV1.5 C-TERMINUS. Ching-Chieh Tung,
Ricardo E. Rivera-Acevedo,
Bernd R. Gardill
, Filip Van Petegem
2912-P
os
B
oard
B342
FUNCTIONAL CONSEQUENCES OF A NOVEL NAV1.9
MUTATION (L1302F) CAUSING CONGENITAL INSENSITIVITY
TO PAIN.
Carlos G. Vanoye
, Tatiana V. Abranova, Chris C. Ramdoski,
Paul Goldberg, Charles J. Cohen, Alfred L. George
2913-P
os
B
oard
B343
INFANT SUDDEN DEATH: NOVEL MUTATIONS RESPONSIBLE
FOR IMPAIRED NAV1.5 CHANNEL FUNCTION. Jace Morganstein,
Kundan Jana, Monique N. Foster, Tomoe Y. Nakamura, Thomas V.
McDonald, Yingying Tang,
William A. Coetzee
2914-P
os
B
oard
B344
BIOPHYSICAL AND MOLECULAR ANALYSIS OF THE SODIUM
CURRENT IN HUMAN INDUCED PLURIPOTENT STEM
CELL-DERIVED CARDIOMYOCYTES. Brian K. Panama, Robert
J. Goodrow, Serge Sicouri, Charles Antzelevitch, Jacqueline A. Treat,
Jonathan M. Cordeiro
2915-P
os
B
oard
B345
NAV1.5 C-TERMINAL DOMAINS INFLUENCE CALCIUM
REGULATION OF FAST INACTIVATION SEPARATELY FROM
CALMODULIN INTERACTION.
Franck Potet
, Svetlana Stepanovic,
Sabina Kupershmidt, Alfred L. George, Jr
2916-P
os
B
oard
B346
CAMKII-DEPENDENT REGULATION OF CARDIAC SODIUM
CHANNEL.
Federica Farinelli
, Deborah DiSilvestre, Peihong Dong,
Yanli Tian, Gordon Tomaselli
2917-P
os
B
oard
B347
RECRUITMENT OF CALMODULIN TO THE TAIL OF THE
VOLTAGE-GATED SODIUM CHANNEL NAV1.2.
Liam Hovey
,
Corinne Andresen, Dagan Marx, Madeline Shea
2918-P
os
B
oard
B348
COUPLING COMPARTMENTAL MODELS TO LIVE NEURONS
TO INVESTIGATE ACTION POTENTIAL MECHANISMS.
Marco A. Navarro
, Sarah L. Debs, Lorin S. Milescu
2919-P
os
B
oard
B349
OPTIMIZING A NAV1.5 MARKOV-MODEL WITH A GENETIC
ALGORITHM.
Zach R. Teed
, Arie Krumholtz, Jonathon R. Silva
2920-P
os
B
oard
B350
RATE CONSTANT MODELS CANNOT DESCRIBE MOVEMENT
OF CHARGED ATOMS OR MOLECULES.
Bob Eisenberg
Voltage-gated Ca Channels
(Boards B351-B370)
2921-P
os
B
oard
B351
TARGETING T-TYPE CHANNELS WITH PROTXII-LIKE
TOXINS.
Autoosa Salari
, Mirela Milescu
2922-P
os
B
oard
B352
ENGINEERING SELECTIVITY IN RGK PROTEIN INHIBITION
OF CAV1/CAV2 CHANNELS.
Akil Puckerin
2923-P
os
B
oard
B353
international
travel awardee
VENTRICULAR L-TYPE CA
2+
CHANNELS AND EXPRESSION
OF RGK PROTEINS IN MOUSE MODELS ASSOCIATED WITH
DIABETES.
Jessica Köth
, Christian Fabisch, Stefan Herzig, Jan Matthes
2924-P
os
B
oard
B354
INHIBITION OF HUMAN CA
V
2.3 CHANNELS VIA μ-,
δ
- AND
κ
-OPIOID RECEPTOR ACTIVATION. Geza Berecki, Leonid Motin,
David J. Adams
2925-P
os
B
oard
B355
CONTROL OF FUNCTIONAL TARGETING OF CAV1.2
CHANNELS BY THE
Γ
6.
Roman Shirokov
, Thomas Comollo, Rose
Rendon
2926-P
os
B
oard
B356
L-TYPE CA
2+
CHANNEL CAVB SUBUNITS ASSOCIATE WITH
AND DIFFERENTIALLY REGULATE THE CARDIAC CAV3.2
T-TYPE CA
2+
CHANNEL CURRENTS.
Marites T. Woon
, Ravi C.
Balijepalli
2927-P
os
B
oard
B357
HOMOLOGOUS SERINE/THREONINE IN THE CA
V
2.2
α
1
AND
2.3
α
1
SUBUNITS BEHAVE SIMILARLY, AS STIMULATORY AND
INHIBITORY PKC SITES.
Ganesan L. Kamatchi
2928-P
os
B
oard
B358
NOREPINEPHRINE UPREGULATES T-TYPE CALCIUM
CHANNELS IN RAT PINEALOCYTES.
Haijie Yu
, Jong Bae Seo,
Seung-Ryoung Jung, Duk-Su Koh, Bertil Hille
2929-P
os
B
oard
B359
SINGLE-CHANNEL ANALYSIS OF THE INHIBITION OF THE
CALCIUM DEPENDENT INACTIVATION BY THE C-TERMINAL
MODULATOR DOMAIN OF CAV1.3 CHANNELS.
Elza
Kuzmenkina
, Elena Novikova, Wanchana Jangsangthong, Stefan Herzig
2930-P
os
B
oard
B360
SERUM FACTOR ALTERS T-TYPE CAV3.2 GATING KINETICS
AND CURRENT DENSITY.
Gray Evans
, Slobodan M. Todorovic
2931-P
os
B
oard
B361
CONVERGENT MODULATIONS BY CARBOXYL-TERMINI
ACROSS L-TYPE CALCIUM CHANNEL SUBTYPES.
Yaxiong Yang
,
Min Liu, Nan Liu, Xiaodong Liu
2932-P
os
B
oard
B362
MODAL BIFURCATION OF CAV1.3 SIGNALING IN CORTICAL
NEURONS.
Min Liu
, Yaxiong Yang, Nan Liu, Ji Tang, Xuyang Sun,
Xiaodong Liu
2933-P
os
B
oard
B363
THE EFFECT OF AUTISM CANDIDATE-GENE MUTATIONS IN
THE VOLTAGE-GATED CALCIUM CHANNEL
β
2 SUBUNIT ON
SINGLE CHANNEL KINETICS.
Alexandra F. Breitenkamp
, Ajay K.
Singh, Vincent Mortier, Patrick Despang, Marion Brill, Elza Kuzmenkina,
Stefan Herzig
2934-P
os
B
oard
B364
DIVERGENT REGULATION OF CARDIOMYOCYTE CAV1.2
CURRENTS BY CALMODULIN MUTANTS ASSOCIATED WITH
HUMAN SUDDEN DEATH SYNDROMES.
Dmytro O. Kryshtal
,
Hyun S. Hwang, Christopher N. Johnson, Walter J. Chazin, Alfred L.
George Jr., Bjorn C. Knollmann