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163

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

W

E

D

N

E

S

D

A

Y

2794-P

os

B

oard

B224

VIRUS-MIMICKING POLYMER MOLECULAR BRUSHES ARE

POTENT ANTIBIOTICS WITH DOUBLE SELECTIVITY. Yunjiang

Jiang, Wan Zheng, Hairong Ma,

Hongjun Liang

2795-P

os

B

oard

B225

ANALYSIS OF PISCIDIN AND LIPOPOLYSACCHARIDE

INTERACTIONS: A STEP TOWARDS CHARACTERIZING

IMMUNOMODULATION.

Laura McCormick

, Myriam Cotten

2796-P

os

B

oard

B226

STUDYING THE MECHANISMS OF HYBRID PEPTIDES

CONTAINING PERMEABALIZING AND CELL PENETRATING

DOMAINS.

Maria A. LaBouyer

, Donald E. Elmore

2797-P

os

B

oard

B227

BINDING OF DAPTOMYCIN TO LIPID BILAYERS IS NOT

SIGNIFICANTLY ALTERED BY THE INCLUSION OF LYSYL-

PHOSPHATIDYLGLYCEROL. Tala Khatib, Hannah Lineberry, Heather

Stevenson, Bayer S. Arnold, Michael R. Yeaman,

Antje Pokorny

Proteins, Lipids, and Small Molecules

(Boards B228-B243)

2798-P

os

B

oard

B228

PHOSPHATIDYLSERINE, A LIPID PRESENT AT THE OUTER

MEMBRANE LEAFLET OF CANCER CELLS, HINDERS

THE INSERTION OF PHLIP, A POTENTIAL CANCER CELL

MARKER.

Haden Scott

2799-P

os

B

oard

B229

UNDERSTANDING MOLECULAR COMPLEXITY IN PROTEIN

AND PEPTIDE-LIPID SYSTEMS. Hannah M. Britt, Vian S. Ismail,

Aruna S. Prakash, Jackie A. Mosely,

John M. Sanderson

2800-P

os

B

oard

B230

PHLIP® TARGETING AND DELIVERY OF PNA TO SILENCE

MICRORNA IN TUMOR CELLS§.

Donald M. Engelman

,

Christopher J. Cheng, Raman Bahal, Imran A. Babar, Zachary Pincus,

Francisco N. Barrera, Connie Liu, Alexander Svoronos, Demetrios T.

Braddock, Peter M. Glazer, W Mark Saltzman, Frank J. Slack

2801-P

os

B

oard

B231

MEMBRANE CHOLESTEROL ASSOCIATION AND STRUCTURE

OF TWO LEUKOTOXIN PEPTIDES.

Cayla M. Miller

, Angela C.

Brown, Jeetain Mittal

2802-P

os

B

oard

B232

CHOLESTEROL ACCESSIBILITY SENSING BY PERFRINGOLYSIN

O DERIVATIVES IS LINKED TO CHANGES IN THE SIZE OF THE

OLIGOMER. Benjamin B. Jonhson, Robert J.C. Gilbert,

Alejandro P. Heuck

2803-P

os

B

oard

B233

FREE ENERGIES FOR TRANS-MEMBRANE PORE FORMATION

IN THE PRESENCE OF ARGININE-RICH PEPTIDES FROM

MOLECULAR DYNAMICS SIMULATIONS.

Neha Awasthi

, Jochen

S. Hub

2804-P

os

B

oard

B234

RESPONSE OF GWALP TRANSMEMBRANE PEPTIDES TO

INCORPORATION OF BURIED HISTIDINE RESIDUES.

Ashley N. Martfeld

, Denise V. Greathouse, Roger E. Koeppe

2805-P

os

B

oard

B235

INFLUENCE OF CHOLESTEROL ON SINGLE ARGININE-

CONTAINING TRANSMEMBRANE HELICAL PEPTIDES.

Jordana K. Thibado

, Ashley N. Martfeld, Denise V. Greathouse, Roger

E. Koeppe

2806-P

os

B

oard

B236

INFLUENCE OF A POTENTIALLY DESTABILIZING CENTRAL

TRYPTOPHAN ON TRANSMEMBRANE HELIX DOMAINS.

Vasu Suresh Kumar

, Ashley N. Martfeld, Denise V. Greathouse, Roger E.

Koeppe

2807-P

os

B

oard

B237

IONIZATION-DEPENDENT BEHAVIOR OF TRANSMEMBRANE

HELICES THAT INCORPORATE GLU OR TYR

RESIDUES.

Venkatesan Rajagopalan

, Denise V. Greathouse, Roger E.

Koeppe

2808-P

os

B

oard

B238

DETECTION OF HELIX FRAYING IN DESIGNED

TRANSMEMBRANE ALPHA HELICES.

Armin Mortazavi

,

Venkatesan Rajagopalan, Denise V. Greathouse, Roger E. Koeppe

2809-P

os

B

oard

B239

COMPARING PEPTIDE-LIPID INTERACTIONS AND

ANTIMICROBIAL ACTIVITIES OF PEPTIDES WITH SIMILAR

“CORE” LENGTHS BUT VARIABLE ARGININE AND

TRYPTOPHAN RESIDUES.

Sara E. Whitlock

, Roger E. Koeppe II,

Denise A. Greathouse

2810-P

os

B

oard

B240

CHARACTERIZATION OF MAXIMIN 3 STRUCTURE AND

MEMBRANE LEAKAGE. Brian Herbst, Jillian Glatz,

Elizabeth Middleton

2811-P

os

B

oard

B241

CHARACTERIZATION OF MEMBRANE INTERACTIONS OF

ANTIMICROBIAL LACTOFERRICIN PEPTIDES WITH CENTRAL

RESIDUE SUBSTITUTIONS.

Amanda Lowe

, Denise V. Greathouse

2812-P

os

B

oard

B242

PROMOTION OF COALESCENCE IN BICELLAR MIXTURES

BY AN SP-B FRAGMENT.

Chris Miranda

, Valerie Booth, Michael R.

Morrow

2813-P

os

B

oard

B243

LIPID COMPOSITION INFLUENCES THE INSERTION AND

FOLDING OF PHLIP PEPTIDES.

Alexander G. Karabadzhak

,

Dhammika Weerakkody, Oleg A. Andreev, Yana K. Reshetnyak, Donald

M. Engelman

Protein-Lipid Interactions III

(Boards B244-B269)

2814-P

os

B

oard

B244

international

travel awardee

ENHANCED HIV FUSION INHIBITORS EFFICACY REQUIRES

MEMBRANE AFFINITY AND EXPOSURE OF THE POCKET

BINDING DOMAIN OF C34 DERIVATIVES.

Marcelo T. Augusto

,

Axel Hollmann, Miguel A. R. B. Castanho, Matteo Porotto, Antonello

Pessi, Nuno C. Santos

2815-P

os

B

oard

B245

education

travel awardee

STRENGTH, NOT DEPTH: AN EXPLORATION OF

DIFFERENTIAL MEMBRANE BINDING KINETICS OF

SYNAPTOTAGMIN-1 AND SYNAPTOTAGMIN-7 C2

DOMAINS.

Joshua V. Vermaas

, Emad Tajkhorshid