158
Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
2672-P
os
B
oard
B102
GEOMETRIC DESCRIPTION OF DYNAMIN INDUCED
MEMBRANE FISSION. Pablo Vázquez-Montejo,
Zachary McDargh
,
Markus Deserno
2673-P
os
B
oard
B103
TWO PATHWAYS MEDIATE INTER-DOMAIN ALLOSTERIC
REGULATION IN PIN1.
Jingjing Guo
, Xiaodong Pang, Huan-Xiang
Zhou
2674-P
os
B
oard
B104
THE IMPACT OF PERTURBING DYNAMIC AMINO ACID
NETWORKS IN A (
β
/
α
)8 BARREL ENZYME.
Kathleen F. O’Rourke
,
Jennifer M. Axe, Nicole E. Kerstetter, David D. Boehr
2675-P
os
B
oard
B105
CONFORMATIONAL EXCHANGE COUPLED TO
IONIZATION OF LYS RESIDUES BURIED IN HYDROPHOBIC
ENVIRONMENTS IN PROTEINS.
Daniel E. Richman
, Ananya
Majumdar, Bertrand Garcia-Moreno
2676-P
os
B
oard
B106
NMR INVESTIGATION OF ENERGY BARRIERS FOR
HYDROGEN-BOND BREAKAGE OF PROTEIN SIDE-CHAIN
NH3+ GROUPS.
Levani Zandarashvili
, Junji Iwahara
2677-P
os
B
oard
B107
THUMB II SITE INHIBITOR ALLOSTERICALLY SUPPRESSES
THE DYNAMICS OF HCV RNA-DEPENDENT RNA
POLYMERASE.
Daniel J. Deredge
, Kenneth Johnson, Patrick Wintrode
2678-P
os
B
oard
B108
DYSFUNCTIONAL CONFORMATIONAL DYNAMICS
OF PROTEIN KINASE A FROM R14 DELETION OF
PHOSPHOLAMBAN.
Jonggul Kim
, Larry R. Masterson, Alessandro
Cembran, Raffaello Verardi, Lei Shi, Jiali Gao, Gianluigi Veglia
2679-P
os
B
oard
B109
DYNAMICAL X-RAY SINGLE MOLECULE OBSERVATIONS
OF THE MOLECULAR RECOGNITION PROCESS IN MAJOR
HISTOCOMPATIBILITY COMPLEX MOLECULE.
Toshihiro Miyabe
, Yufuku Matsushita, Kosuke Kasadera, Yuko Kozono,
Hiroshi Sekiguchi, Keigo Ikezaki, Haruo Kozono, Yuji C. Sasaki
2680-P
os
B
oard
B110
UNEXPECTED VASP-EVH1 INTERACTIONS WITH IRAK1 AND
ZYXIN: PHOSPHORYLATION AND BIVALENT BINDING.
Lucila A. Acevedo
, Alex I. Greenwood, Jeahoo Kwon, Kun P. Lu, Linda
K. Nicholson
2681-P
os
B
oard
B111
INFLUENCE OF RNA BINDING ON THE CONFORMATIONAL
DYNAMICS OF THE LASSA VIRUS NUCLEOPROTEIN.
Jason Pattis
, Eric R. May
2682-P
os
B
oard
B112
SITE-SPECIFIC CONFORMATIONAL DIVERSITY IN
CALMODULIN USING CYANYLATED CYSTEINE VIBRATIONAL
PROBES ALONG ITS BINDING INTERFACES.
Kristen L. Kelly
,
Rebecca Wai, Kanika Ramchandani, Casey Londergan
2683-P
os
B
oard
B113
BACKBONE FLEXIBILITY AS A DETERMINANT OF PKA VALUES
OF BURIED IONIZABLE GROUPS IN PROTEINS.
Bertrand Garcia-Moreno
, Gabrieal Ortega, Meredith T. Peck, Aaron
Robinson, Jamie L. Schlessman
2684-P
os
B
oard
B114
REGULATION OF THE MOLECULAR BRAKE REGION IN FGFR2
KINASE.
Jerome M. Karp
, David Cowburn
2685-P
os
B
oard
B115
PKA VALUES OF BURIED GROUPS IN PROTEINS ARE
SENSITIVE TO THE GLOBAL THERMODYNAMIC
STABILITY.
Jaime L. Sorenson
, Raidizon Mercedes, Jamie L.
Schlessman, Bertrand García-Moreno
2686-P
os
B
oard
B116
CRITICAL ROLE OF A GLYCINE RESIDUE IN AN ALLOSTERIC
SWITCH. Dorothy Beckett,
William Cressman
Enzymes and Protein Dynamics II
(Boards B117-B134)
2687-P
os
B
oard
B117
ZINC INHIBITS HEDGEHOG AUTO
PROCESSING:LINKINGZINC DEFICIENCY WITH HEDGEHOG ACTIVATION.
Jian Xie
,
Timothy Owen, Ke Xia, Ajay Vikram Singh, Emiley Tou, Lingyun Li, Leo
Q. Wan, Brian Callahan, Chunyu Wang
2688-P
os
B
oard
B118
PROBING FACTOR XIII SUBSTRATE SPECIFICITY
FOR FIBRINOGEN
α
C (233-425) USING MALDI-TOF
MASS SPECTROMETRY AND 2D 15N-1H HSQC NMR
SPECTROSCOPY.
Kelly Njine Mouapi
, Jacob Bell, Kerrie Smith, Helen
Philippou, Robert Ariens, Muriel Maurer
2689-P
os
B
oard
B119
LIGAND BINDING TO ANION BINDING EXOSITES
AS PROTHROMBIN IS CONVERTED TO ACTIVE
THROMBIN.
Ramya Billur
, Marina V. Malovichko, Muriel C. Maurer
2690-P
os
B
oard
B120
MOLECULAR DYNAMICS STUDIES OF THE UBIQUITIN
CONJUGATION MECHANISM.
Serban Zamfir
2691-P
os
B
oard
B121
PROTEOLYSIS OF ABNORMAL PRION PROTEIN WITH A
THERMOSTABLE PROTEASE FROM A HYPER-THERMOPHILIC
ARCHAEON THERMOCOCCUS KODAKARENSIS KOD1.
Yuichi Koga
, Nami Shimizu, Akikazu Sakudo, Shigenori Kanaya
2692-P
os
B
oard
B122
KINETIC CHARACTERIZATION OF HUMAN LIVER
PHOSPHOFRUCTOKINASE.
Amanda Tindall
, Gregory D. Reinhart
2693-P
os
B
oard
B123
USE OF 2-PHOTON FLUORESCENCE CORRELATION
SPECTROSCOPY AND ELECTRON MICROSCOPY TO
ELLUCIDATE THE DEPENDENCE OF RLPFK SELF
ASSOCIATION ON LIGAND CONCENTRATION.
David Holland
,
Jeng-Yih Chang, Junjie Zhang, Gregory D. Reinhart
2694-P
os
B
oard
B124
THE ISOLATED LARGE SUBUNIT OF E. COLI
CARBAMOYLPHOSPHATE SYNTHETASE DEVIATES FROM
KINETIC MECHANISM AND ALLOSTERIC BEHAVIOR OF THE
HOLOENZYME.
Robert Koenig
, Gregory D. Reinhart
2695-P
os
B
oard
B125
FREE-ENERGY LANDSCAPES OF THE TRANSLOCATION
OF A SUBSTRATE IN FOUR PROTEASOME - ACTIVATOR
COMPLEXES ANALYZED USING MOLECULAR DYNAMICS
SIMULATIONS.
Hisashi Ishida