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157

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

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Protein Assemblies II (Boards B77-B98)

2647-P

os

B

oard

B77

ASSEMBLY OF THE RIG-I 2CARD SIGNALING COMPLEX.

David Mouser

2648-P

os

B

oard

B78

CHARACTERIZATION OF THE MDA5 2CARD SIGNALING

COMPLEX.

Cassie Zerbe

, James Cole

2649-P

os

B

oard

B79

DETAILED MECHANISM OF RAPID AMYLOID FIBRIL SELF-

ASSEMBLY DUE TO SURFACE DIFFUSION.

Yi-Chih Lin

, E. James

Petersson, Zahra Fakhraai

2650-P

os

B

oard

B80

CO-AGGREGATION OF ALPHA-SYNUCLEIN WITH

AMYLIN(HIAPP) LEADS TO AN INCREASED RISK IN TYPE

II DIABETES PATIENTS FOR DEVELOPING PARKINSON’S

DISEASE.

Yoav Atsmon-Raz

, Yifat Miller

2651-P

os

B

oard

B81

INSIGHT INTO THE METAL BINDING SITES IN AMYLIN

AGGREGATES. Vered Wineman-Fisher,

Yifat Miller

2652-P

os

B

oard

B82

CHARACTERIZING KINETIC INTERMEDIATE IN AMYLOID

SELF-ASSEMBLY.

Chen Liang

2653-P

os

B

oard

B83

SITE-SPECIFIC STRUCTURAL CHANGES IN UNMODIFIED

AND PYROGLUTAMYLATED AMYLOID BETA PEPTIDE BY

ISOTOPE-EDITED FTIR.

Greg Goldblatt

, Jason O. Matos, Jeremy

Gornto, Laura N. Puentes, Angel Docobo, Suren A. Tatulian

2654-P

os

B

oard

B84

PREPARATION PROTOCOLS OF BETA-AMYLOID (1-

40) PROMOTE THE FORMATION OF POLYMORPHIC

AGGREGATES AND ALTERED INTERACTIONS WITH LIPID

BILAYERS.

Elizabeth A. Yates

, Justin Legleiter

2655-P

os

B

oard

B85

THERMODYNAMICS OF ABETA(16-21) DISSOCIATION FROM

AN AMYLOID FIBRIL.

Cristiano L. Dias

, Srinivasa Rao Jampani

2656-P

os

B

oard

B86

A COMPUTATIONAL STUDY OF AMYLOID

β

-PROTEIN

ASSEMBLY IN CROWDED ENVIRONMENTS.

Matthew J. Voelker

,

Brigita Urbanc, Mark Betnel

2657-P

os

B

oard

B87

TRANSITION OF AMYLOID OLIGOMERS TO MATURE FIBRILS:

INTERNAL CONVERSION VS. COMPETING ASSEMBLY

PATHWAYS?

Tatiana Miti

, Mentor Mulaj, Martin Muschol

2658-P

os

B

oard

B88

STRUCTURAL VARIATIONS OF AMYLOID

β

-PROTEIN FIBRILS

SEEDED WITH EXTRACTED FIBRILS FROM BRAIN TISSUE OF

ALZHEIMER’S DISEASE MODEL MICE.

Hiroaki Komatsu

, Paul H.

Axelsen

2659-P

os

B

oard

B89

DETERMINATION OF NUCLEATION MASS FOR AMYLOID-

β

AGGREGATION. Preetam Ghosh, Amit Kumar, Vijayaraghavan

Rangachari,

Ashwin Vaidya

2660-P

os

B

oard

B90

MORPHOLOGY SELECTION THROUGH GEOMETRIC

FRUSTRATION IN TWISTED FILAMENT BUNDLES AND

FIBERS. Doug Hall,

Isaac R. Bruss

, Justin Barone, Gregory M. Grason

2661-P

os

B

oard

B91

NOVEL SINGLE-MOLECULE RESOLUTION METHOD FOR

SPATIO-TEMPORAL SIMULATIONS OF PROTEIN BINDING

AND RECRUITMENT ON THE MEMBRANE.

Osman N. Yogurtcu

,

Margaret E. Johnson

2662-P

os

B

oard

B92

STOICHIOMETRY AS A KEY MODULATOR OF PIP PLANT

AQUAPORINS BIOLOGICAL ACTIVITY.

Cintia Jozefkowicz

, Lorena

Sigaut, Agustina Canessa Fortuna, Florencia Scochera, Luis González

Flecha, Lia I. Pietrasanta, Nicolás D. Ayub, Gabriela Soto, Gabriela

Amodeo, Karina Alleva

2663-P

os

B

oard

B93

LANDSCAPES OF MEMBRANE PROTEIN INTERACTIONS

FROM HIGH-THROUGHPUT MD SIMULATIONS USING

THE DAFT APPROACH.

Tsjerk A. Wassenaar

, Kristyna Pluhackova,

Anastassiia Moussatova, Durba Sengupta, Siewert J. Marrink, D. Peter

Tieleman, Rainer A. Böckmann

2664-P

os

B

oard

B94

INCREASED SIGNALING EFFICIENCY OF CONVENTIONAL

PKC THROUGH SELF-ASSEMBLED CLUSTERING ON THE

PLASMA MEMBRANE. Xin Hui, Mike Bonny, Lars Kaestner, Karsten

Kruse,

Peter Lipp

2665-P

os

B

oard

B95

DEVELOPMENT OF TOOLS TO STUDY RETROVIRAL GAG

ASSEMBLY ON GIANT UNILAMELLAR VESICLES(GUV).

Yi Wen

,

Robert Dick, Volker Vogt, Gerald Feigenson

2666-P

os

B

oard

B96

PARADIGM SHIFT IN THE MECHANISM OF HIV-1 CORE

BIOGENESIS.

Gabriel A. Frank

, Kedar Narayan, Julian W. Bess Jr,

Gregory Q. Del Prete, Xiongwu Wu, Amy Moran, Lisa Hartnell, Lesley A.

Earl, Jeffrey D. Lifson, Sriram Subramaniam

2667-P

os

B

oard

B97

education

travel awardee

MOLECULAR DYNAMICS AND ASSEMBLY SWITCH OF FTSZ

FILAMENTS.

Erney Ramírez-Aportela

, José Ramón López-Blanco, José

Manuel Andreu, Pablo Chacon

2668-P

os

B

oard

B98

STRUCTURAL AND BIOPHYSICAL COMPARISON OF UPEC

AND ETEC ADHESION FIMBRIAE. Narges Mortezaei, Bhupender

Singh,

Esther Bullitt

, Johan Zakrisson, Chelsea R. Epler, Krister

Wiklund, Magnus Andersson

Protein Dynamics and Allostery III

(Boards B99-B116)

2669-P

os

B

oard

B99

PROPOSED THERMODYNAMIC BASIS FOR SYNAPTOTAGMIN

RESPONSE.

Anne Hinderliter

2670-P

os

B

oard

B100

ALLOSTERIC FUNCTIONAL SWITCH IN POLIOVIRUS 3C

PROTEASE.

Yan M. Chan

, David D. Boehr

2671-P

os

B

oard

B101

THE STRUCTURAL BASIS OF ATP AS AN ALLOSTERIC

MODULATOR.

Shaoyong Lu

, Wenkang Huang, Qi Wang, Qiancheng

Shen, Shuai Li, Ruth Nussinov, Jian Zhang