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S281

ESTRO 36 2017

_______________________________________________________________________________________________

angle, MLC position, and MU were 0.16° ± 0.01° (range,

0.12°–0.17°), 0.08° ± 0.00° (range, 0.0.7°–0.08°), 0.08 ±

0.02 mm (range, 0.04–0.11 mm), and 0.37 ± 0.05 MU

(range, 0.30–0.44 MU), respectively. In the delivered dose

reconstruction, the means ± SDs of the dose difference of

the all dose-volumetric indices were 0.5% ± 0.8% (range,

0.0%–4.2%) and 0.2% ± 0.2% (range, 0.0%-0.7%) for the

brain and prostate tumors, respectively.

Conclusion

We have established patient-specific QA procedure for the

DWA using ArcCHECK and log files. Our results have shown

that DWA with Vero4DRT delivered the accurate dose

distribution.

OC-0535 Multicenter validation of ion chambers in

reference dosimetry of two IORT-dedicated electron

linacs

P. Scalchi

1

, G. Felici

2

, A. Ciccotelli

2

, A. Petrucci

3

, V.

Piazzi

4

, N. Romeo

5

, A. Pentiricci

6

, F. Cavagnetto

7

, S.

Andreoli

8

, F. Cattani

9

, S. Fabbri

10

, P. Tabarelli de Fatis

11

,

R. Romagnoli

12

, A. Soriani

13

, B. Augelli

14

, M. Paolucci

15

, P.

D'Avenia

16

, M. Bertolini

17

, R. Massafra

18

, E. Moretti

19

, S.

De Stefano

2

, L. Grasso

2

, C. Baiocchi

20

, P. Francescon

1

1

Ospedale San Bortolo, MEDICAL PHYSICS, Vicenza, Italy

2

SIT, R&D, Aprilia, Italy

3

S. Filippo Neri Hospital, MEDICAL PHYSICS, Rome, Italy

4

Multimedica Hospital, RADIOTHERAPY, Castellanza,

Italy

5

S. Vincenzo Hospital- ASL Messina, RADIOTHERAPY,

Taormina, Italy

6

ASL Umbria 1, RADIOTHERAPY, Città di Castello, Italy

7

IRCCS A.O.U. SAN MARTINO-IST, MEDICAL PHYSICS,

Genova, Italy

8

ASST Papa Giovanni XXIII, MEDICAL PHYSICS, Bergamo,

Italy

9

European Institute of Oncology, MEDICAL PHYSICS,

Milan, Italy

10

S.Anna University-Hospital, MEDICAL PHYSICS, Ferrara,

Italy

11

Fondazione Salvatore Maugeri, MEDICAL PHYSICS,

Pavia, Italy

12

Bellaria Hospital, MEDICAL PHYSICS, Bologna, Italy

13

National Cancer Istitute Regina Elena, Laboratory of

Medical Physics and Expert System, Rome, Italy

14

Spoleto Hospital- A.U.S.L. Umbria 2, RADIOTHERAPY,

Spoleto, Italy

15

Foligno Hospital- A.U.S.L. Umbria 2, MEDICAL PHYSICS,

Foligno, Italy

16

ASUR MARCHE AV3, MEDICAL PHYSICS, Macerata, Italy

17

Arcispedale S. Maria Nuova-I.R.C.C.S., MEDICAL

PHYSICS, Reggio Emilia, Italy

18

I.R.C.C.S. Institute of Oncology Giovanni Paolo II,

MEDICAL PHYSICS, Bari, Italy

19

“Santa Maria della Misericordia" University-Hospital,

MEDICAL PHYSICS, Udine, Italy

20

Ospedale San Bortolo, RADIOTHERAPY, Vicenza, Italy

Purpose or Objective

LIAC and NOVAC (SIT, Italy) are two mobile linacs

dedicated to IORT generating electron beams in the

energy range of 3-12 MeV. Due to the large amount of

scattered electrons from the collimator walls inside the

IORT field, their energy spectra are very different from

the traditional linacs on which are based the international

dosimetry protocols. In addition, the methods

recommended by these protocols to determine the ion-

recombination correction factor (k

s

) fail under these high

dose-per-pulse beams. Hence in 2003 the Italian Health

Institute stated that ion chambers cannot be used for

reference dosimetry of these linacs. Based on a

retrospective multi-center survey, a comparison with

ferrous sulphate dosimetry is now used to validate

parallel-plate ion chambers for this purpose.

Material and Methods

17 centers participating in this study had modified the

IAEA TRS-398 dosimetry protocol regarding the reference

irradiation setup and the determination of k

s

, for which a

previously published method, independent of ferrous

sulphate dosimetry, was adopted. Ferrous sulphate

dosimeters and ion chambers had been irradiated in water

phantoms. When both were positioned at the depth of

maximum dose the beam-quality correction factor k

Q,Qo

was renormalized based on water-air stopping power

ratios. The equivalence between the dosimetry systems

was checked by verifying the deviations Δ

ic-fs

between ion

chambers and ferrous sulphate dosimetry together with

the associated uncertainties.

Results

The mean Δ

ic-fs

is -0.5% with an uncertainty of ±0.9%, which

shows no systematic deviations between systems. Δ

ic-fs

dispersion is 3.9% (2σ). 40% of the Δ

ic-fs

are within ±1%, 70%

within ±2% and 90% within ±3%.No significant dependence

on electron energy was found, thus confirming k

Q,Qo

renormalization. The influence of both chamber type and

polarizing voltage on k

s

was also analyzed. Ion chambers

with lower electrode spacing or polarizing voltages higher

than the normal operating ones allows a reduction of k

s

,

providing the chamber performance at these voltages has

previously been checked for linearity of 1/Q versus 1/V.

Conclusion

Parallel-plate ionization chambers can properly and

accurately substitute ferrous sulphate detectors in

reference dosimetry of LIAC and NOVAC mobile linacs.

Therefore, we hope that the main dosimetry protocols for

reference dosimetry in external-beam radiotherapy will

provide guidance in the calibration of electron beams from

linacs dedicated to IORT.

Proffered Papers: Novel methods for auditing

OC-0536 Causes of irradiation failures of IROC

Houston’s IMRT credentialing phantom

S. Kry

1

, J. Kerns

1

, M. Carson

1

, A. Molineu

1

, P. Taylor

1

, D.

Followill

1

1

UT MD Anderson Cancer Center Radiation Physics,

Radiation Physics, Houston- TX, USA