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Detection
Structural Functional
element
• Relatively easy to detect
• Presence or absence
• Often qualitative
• inexpensive
• Relatively Not-easy to detect
• Active or inactive
• Qualitative and quantitative
• Expensive
• Representative of BoNT intoxication
Types of testing
Mouse assay
(detection of
functional toxin)
toxin screening
toxin titer
toxin neutralization
by using antitoxin