Test parameters
•
Sensitivity:
–
the ability to identify as positive all those with the disease
•
Specificity:
–
the ability to identify as negative all those without the
disease
•
Predictive value positive (PV+):
–
the proportion of true positives among those testing
positive
•
Predictive value negative (PV-):
–
the proportion of true negatives among those testing
negative
Disease
present
absent
a=true
positives
b=false
positives
c=false
negatives
d=true
negatives
Test
result
POS
NEG
total
a+b
c+d
TOT
a+c
b+d
Sensitivity = a/ (a+c)
Specificity = d/ (b+d)
PV+ = a/ (a+b)
PV- = d/ (c+d)