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Selective mediastinal irradiation

• The high negative predictive value of PET for mediastinal lymph

nodes, can be exploited by irradiating only PET-positive areas

• Selective mediastinal node irradiation results in low isolated nodal

failure rates

De Ruysscher et al. 2005; Int.

J. Radiat. Oncol. Biol. Phys.

62:998-994