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• uptake of FDG in inflamatory sites
• false negative PET after
chemotherapy
• small lesions (< 1 cm3) may not be
seen
• Respiratory motion causes blurring
of image in 3D PET
free-breathing
gated
Nehmeh et al. 2004; Med.
Phys. 31:3179-3186
Limitations of PET for staging of lung cancer