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PET(-CT) for staging of lung cancer

• PET improves accuracy of staging

– High negative predictive value of PET for mediastinal lymph

nodes

• Improved staging has impact on treatment strategy

– Selective irradiation of mediastinum based on PET results in

low rates of nodal failure

• Residual FDG uptake after treatment correlates with

location of high uptake pre-treatment and is

associated with worse outcome

• What is the impact of PET on delineation?