1166 / 2351
5/30/16
13
3*
14**
–
2
Infusion reaction#
4
52
5
50
Fatigue/Malaise
4
64
3
70
Xerostomia
25
64
30
63
Dysphagia
54
91
52
93
Mucositis/Stomatitis
34**
97*
18
91
Skin reaction
Gr. 3/4
All Gr.
Gr. 3/4
All Gr.
% Toxicity
RT+E (N=208)
RT (N=212)
#
Listed for its relationship to cetuximab
* p < 0.05, ** p < 0.001, Fisher’s exact test
Bonner, NEJM, 2006
EGF-R inhibitor and RxTh in HNSCC: toxicity
EHNS-ESTRO H&N course
Florence, June 2016
Segaert S, Van Cutsem E. Ann Oncol, 2005
Skin rash with EGFR-inhibiteur
EHNS-ESTRO H&N course
Florence, June 2016