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SQUAMOUS CELL CARCINOMA NOS ( 80 - 90% )
size of neoplastic cell
basaloid morphology
keratinization
presence of mucinous microcysts
ANAL CARCINOMA : HISTOLOGICAL
CLASSIFICATION
WHO 2
nd
Edition.
large cell keratinizing
large cell non-keratinizing
Basaloid ( cloacogenic )
degree of differentiation
presence of adjacent AIN
•
VERRUCOUS CARCINOMA
( GIANT CONDYLOMA OF BUSCHKE-LOWENSTEIN )
( < 1 % )
•
ADENOCARCINOMA
( anal gland, mucinous – fistula related, rectal type )
( 10 – 15 % )
•
NEUROENDOCRINE CARCINOMA ( large cell & small cell type ) ( < 2 % )