301 / 1068
study
No. Time period treatment outcome
Boman et al ( 1984 )
SCC – grades 1 to 4
Basaloid type SCC
188 1950-1976 Surgery
Grade & type correlated with
stage.
No significant correlation with
survival after adjusting for stage.
Dougherty et al ( 1984 )
Keratinizing SCC
Non-keratinizing SCC
Basaloid SCC
SCC with microcysts
79 Pre 1978 Surgery
No correlation of histologic type
with depth of invasion or node
metastasis.
No correlation with survival.
Shepherd et al (1989)
SCC
Basaloid type
235 1948-1985 Surgery
Histologic type not predictive of
survival in multivariate analysis.
Mixed type
Bartelink et al (1997)
SCC versus other types
Histologic grade
110 1987-1994 RT & CRT
Neither type nor grade predicted
local control or survival.
Myerson et al (2001)
SCC – low & high grade
Basaloid type
106 1975-1997 Mainly
CRT
Borderline significant improved
5yr DFS for basaloid type.
No effect of tumour grade.
Das et al (2007)
SCC grades 1 to 3
Basaloid type
167 1992-2004 CRT
Basaloid type associated increased
risk of Distant Metastasis
(HR 4.23)
.
No correlation type or grade with
loco-regional failure or survival.