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The Royal Marsden
Royal Marsden Criteria
1. MRI defined complete response: mrTRG1-2 : low signal
intensity fibrotic scar tissue only seen at MRI performed 4
weeks after long-course CRT, confirmed at 8-12 week MRI.
Biopsy positive disease not an initial exclusion criterion
Thickening of rectal wall – not an exclusion
Abnormality on endoscopy – not an exclusion
Clinically palpable tumour – not an exclusion
PET-CT positivity not an initial exclusion
Persistent DWI signal – not an initial exclusion