414 / 1068
The Royal Marsden
RMH Deferral Trial Entry Criteria
1. MRI defined complete response: mrTRG1-2 : low signal
intensity fibrotic scar tissue only seen at MRI performed 4
weeks after long-course CRT, confirmed at 8-12 week MRI.
Biopsy positive disease not an initial exclusion criterion
Thickening of rectal wall – not an exclusion
Abnormality on endoscopy – not an exclusion
Clinically palpable tumour – not an exclusion
59 patients enrolled in 3 years