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The Royal Marsden

Inclusion criteria

– Tumors within 1 mm of mesorectal fascia (ie,

potential circumferential resection margin

involvement)

– T3 c (extramural spread 5-15 mm) and T3 d

(extramural spread >15 mm), regardless of N stage

– MRI T4a or T4b disease regardless of N stage

– Low rectal cancer with tumor bordering the

intersphincteric/ distal TME plane on MRI

– Tumors with MRI extramural venous invasion

(mrEMVI)