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Version 2.2015, 03/11/15 © National Comprehensive Cancer Network, Inc. 2015, All rights reserved.

The NCCN Guidelines® and this illustration may not be reproduced in any form without the express written permission of NCCN®.

MS-83

NCCN Guidelines Index

Breast Cancer Table of Contents

Discussion

NCCN Guidelines Version 2.2015

Breast Cancer

225. Romond E, Suman V, Jeong J-H, et al. Trastuzumab plus adjuvant

chemotherapy for HER2-positive breast cancer: Final planned joint

analysis of overall survival (OS) from NSABP B-31 and NCCTG N9831.

Cancer Research 2012;72:S5-5. Available at:

http://cancerres.aacrjournals.org/cgi/content/meeting_abstract/72/24_M

eetingAbstracts/S5-5

.

226. Slamon D, Eiermann W, Robert N, et al. Adjuvant trastuzumab in

HER2-positive breast cancer. N Engl J Med 2011;365:1273-1283.

Available at:

http://www.ncbi.nlm.nih.gov/pubmed/21991949

.

227. Cobleigh MA, Vogel CL, Tripathy D, et al. Multinational study of the

efficacy and safety of humanized anti-HER2 monoclonal antibody in

women who have HER2-overexpressing metastatic breast cancer that

has progressed after chemotherapy for metastatic disease. J Clin Oncol

1999;17:2639-2648. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/10561337

.

228. Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy

plus a monoclonal antibody against HER2 for metastatic breast cancer

that overexpresses HER2. N Engl J Med 2001;344:783-792. Available

at:

http://www.ncbi.nlm.nih.gov/pubmed/11248153 .

229. Vogel CL, Cobleigh MA, Tripathy D, et al. Efficacy and safety of

trastuzumab as a single agent in first-line treatment of HER2-

overexpressing metastatic breast cancer. J Clin Oncol 2002;20:719-

726. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/11821453

.

230. Jeffrey SS, Lonning PE, Hillner BE. Genomics-based prognosis

and therapeutic prediction in breast cancer. J Natl Compr Canc Netw

2005;3:291-300. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/16002001

.

231. Perou CM, Jeffrey SS, van de Rijn M, et al. Distinctive gene

expression patterns in human mammary epithelial cells and breast

cancers. Proc Natl Acad Sci U S A 1999;96:9212-9217. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/10430922

.

232. Sorlie T, Perou CM, Tibshirani R, et al. Gene expression patterns

of breast carcinomas distinguish tumor subclasses with clinical

implications. Proc Natl Acad Sci U S A 2001;98:10869-10874. Available

at:

http://www.ncbi.nlm.nih.gov/pubmed/11553815 .

233. Sorlie T, Tibshirani R, Parker J, et al. Repeated observation of

breast tumor subtypes in independent gene expression data sets. Proc

Natl Acad Sci U S A 2003;100:8418-8423. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/12829800

.

234. Paik S, Shak S, Tang G, et al. A multigene assay to predict

recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J

Med 2004;351:2817-2826. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/15591335

.

235. Paik S, Tang G, Shak S, et al. Gene expression and benefit of

chemotherapy in women with node-negative, estrogen receptor-positive

breast cancer. J Clin Oncol 2006;24:3726-3734. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/16720680

.

236. Fan C, Oh DS, Wessels L, et al. Concordance among gene-

expression-based predictors for breast cancer. N Engl J Med

2006;355:560-569. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/16899776

.

237. Wang Y, Klijn JGM, Zhang Y, et al. Gene-expression profiles to

predict distant metastasis of lymph-node-negative primary breast

cancer. Lancet 2005;365:671-679. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/15721472

.

238. Glas AM, Floore A, Delahaye LJMJ, et al. Converting a breast

cancer microarray signature into a high-throughput diagnostic test. BMC

Genomics 2006;7:278-278. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/17074082

.

239. van de Vijver MJ, He YD, van't Veer LJ, et al. A gene-expression

signature as a predictor of survival in breast cancer. N Engl J Med