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Version 2.2015, 03/11/15 © National Comprehensive Cancer Network, Inc. 2015, All rights reserved.

The NCCN Guidelines® and this illustration may not be reproduced in any form without the express written permission of NCCN®.

MS-84

NCCN Guidelines Index

Breast Cancer Table of Contents

Discussion

NCCN Guidelines Version 2.2015

Breast Cancer

2002;347:1999-2009. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/12490681

.

240. van 't Veer LJ, Dai H, van de Vijver MJ, et al. Gene expression

profiling predicts clinical outcome of breast cancer. Nature

2002;415:530-536. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/11823860

.

241. Knauer M, Mook S, Rutgers EJ, et al. The predictive value of the

70-gene signature for adjuvant chemotherapy in early breast cancer.

Breast Cancer Res Treat 2010;120:655-661. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/20204499

.

242. Kunz G. Use of a genomic test (MammaPrint) in daily clinical

practice to assist in risk stratification of young breast cancer patients.

Arch Gynecol Obstet 2011;283:597-602. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/20383789

.

243. Ishitobi M, Goranova TE, Komoike Y, et al. Clinical utility of the 70-

gene MammaPrint profile in a Japanese population. Jpn J Clin Oncol

2010;40:508-512. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/20110242

.

244. Mook S, Knauer M, Bueno-de-Mesquita JM, et al. Metastatic

potential of T1 breast cancer can be predicted by the 70-gene

MammaPrint signature. Ann Surg Oncol 2010;17:1406-1413. Available

at:

http://www.ncbi.nlm.nih.gov/pubmed/20094918 .

245. A phase III, randomized clinical trial of standard adjuvant

endocrine therapy +/-chemotherapy in patients with 1-3 positive nodes,

hormone receptor-positive and HER2-negative breast cancer with

recurence score (RS) of 25 or less. RXPONDER: A clinical trial RX for

positive node, endocrine responsive breast cancer. Clincial Trial ID

NCT01272037. Available at:

http://clinicaltrials.gov/show/NCT01272037

.

246. A phase III, randomized, double-blind, placebo-controlled clinical

trial to evaluate the efficacy and safety of pertuzumab + trastuzumab +

docetaxel vs. placebo + trastuzumab + docetaxel in previously

untreated HER2-positive metastatic breast cancer. Trial

ID:NCT00567190. Available at:

www.clinicaltrials.gov

.

247. MINDACT (Microarray In Node-Negative and 1 to 3 positive lymph

node disease may avoid chemotherapy): A prospective, randomized

study comparing the 70-Gene signature with the common clinical-

pathological criteria in selecting patients for adjuvant chemotherapy in

breast cancer with 0 to 3 positive nodes. Clinical Trial ID:

NCT00433589. Available at:

http://clinicaltrials.gov/ct2/show/NCT00433589?term=NCT00433589&ra

nk=1

.

248. Albain KS, Barlow WE, Shak S, et al. Prognostic and predictive

value of the 21-gene recurrence score assay in postmenopausal

women with node-positive, oestrogen-receptor-positive breast cancer

on chemotherapy: a retrospective analysis of a randomised trial. Lancet

Oncol 2010;11:55-65. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/20005174

.

249. Hormone therapy with or without combination chemotherapy in

treating women who have undergone surgery for node-negative breast

cancer (The TAILORx Trial). Clinical Trial ID: NCT00310180. Available

at:

http://clinicaltrials.gov/ct2/show/NCT00310180?term=TAILORx&rank=2

.

250. Swain SM, Wilson JW, Mamounas EP, et al. Estrogen receptor

status of primary breast cancer is predictive of estrogen receptor status

of contralateral breast cancer. J Natl Cancer Inst 2004;96:516-523.

Available at:

http://www.ncbi.nlm.nih.gov/pubmed/15069113

.

251. Berry DA, Cirrincione C, Henderson IC, et al. Estrogen-receptor

status and outcomes of modern chemotherapy for patients with node-

positive breast cancer. JAMA 2006;295:1658-1667. Available at:

http://www.ncbi.nlm.nih.gov/pubmed/16609087

.

252. Albain KS, Barlow WE, Ravdin PM, et al. Adjuvant chemotherapy

and timing of tamoxifen in postmenopausal patients with endocrine-