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0 6 12 18 24 30 36 42 48 54 60

Time after treatment (months)

0

20

40

60

80

100

Loco-regional control (%)

(heavy)

59%

65%

0 6 12 18 24 30 36 42 48 54 60

Time after treatment (months)

0

20

40

60

80

Overall survival (%)

45%

39%

(moderate)

(no smoking)

66%

52%

Radiotherapy treatment of Head and Neck Carcinoma (233 pts)

DAHANCA

(no smoking)

(moderate)

(heavy)

p=0.002

p=0.008

Smoking and treatment outcome