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Hypofractionation in prostate cancer

• Fractionation sensitivity of prostate tumors is uniquely high (α/β 1.5 Gy)

• The α/β is lower than normal tissues at risk (α/β 3-4 Gy)

Ritter et al. Semin. Radiat. Oncol.

2008

EQD2 in 2 Gy fractions with

α/β 1.5 Gy