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Name

Target

Company

Class

Bevacizumab

VEGF

Genentech

Monoclonal antibody

BIBW 2992 (Tovok)

EGFR and Erb2

Boehringer Ingelheim Small molecule

Cetuximab

EGFR

Imclone/BMS

Monoclonal antibody

Imatinib

Bcr-Abl

Novartis

Small molecule

Trastuzumab

Erb2 (Her2)

Genentech/Roche Monoclonal antibody

Gefitinib

EGFR

AstraZeneca

Small molecule

Ranibizumab

VEGF

Genentech

Monoclonal antibody

Pegaptanib

VEGF

OSI/Pfizer

Small molecule

Sorafenib

Multiple targets

Onyx/Bayer

Small molecule

Dasatinib

Multiple targets

BMS

Small molecule

Sunitinib

Multiple targets

Pfizer

Small molecule

Erlotinib

EGFR

Genentech/Roche Small molecule

Nilotinib

Bcl-Abr

Novartis

Small molecule

Lapatinib

EGFR/Erb2

GSK

Small molecule

Panitumumab

EGFR

Amgen

Monoclonal antibody

+ many more