1542-1543 / 2063
EGFR inhibition + RCT in rectal cancer
•
CRT might have been compromised by cetuximab
pretreatment
•
Pre-CRT initial dose of
cetuximab decreased tumor
cell proliferation
•
Capecitabine needs to
be taken up by proliferating
cells to exert its effects
27
Debucquoy JCO 2009