1764-1765 / 2063
Take home messages
•
If tolerance has already been exceeded: no
re-irradiation possible without loss of function
•
Early effects
–
Low to moderate doses:
•
Restitution of original tolerance may be complete
after tissue-specific and dose-dependent time
intervals
–
High doses:
•
Residual damage may remain for longer intervals,
particular at the stem cell level, which is not
necessarily reflected in functional tissue
compartments
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