1830-1831 / 2063
Ex-vivo assays
•
Clonogenic assays (plating assays)
•
Tumors are excised, reduced to single cells and grown
in a test environment
•
Provide a direct measure of the surviving fraction of
clonogenic cells.
•
Limitation: relationship between clonogens (in test
environment) and stem cells (in situ) is uncertain.
20