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14
ESTRO
2017
REGION
LESION
Brain and spinal cord
Isolated brain metastases
Selected brain tumor recurrences
Pituitary adenomas
Arteriovenous malformations (AVMs)
Base of skull
Meningiomas
Acoustic neuromas
Chordomas and chondrosarcomas
Eye
Uveal melanomas
Macular degeneration
Head and neck
Nasopharynx (primary and recurrent) tumors
Oropharynx (locally advanced) tumors
Paranasal sinus tumors
Chest and abdomen
Medically inoperable non-small-cell lung cancer
Chordomas and chondrosarcomas
Hepatic tumors
Retroperitoneal tumors
Paraspinal tumors
Pelvis
Prostate tumors
Chordomas and chondrosarcomas
Pediatric lesions
Brain and spinal cord tumors
Orbital and ocular tumors
Sarcomas of the base of skull and spine
Abdominal and pelvic tumors
PROTON THERAPY INDICATIONS
Suit, 2010
ESTRO
2017
Comparison between CRT and SBRT for stage I NSCLC
Grutterset al., 2009
Retrospective single arm studies: 1994-2008
30 studies included (2611 patients, published data)
Treatment
#pts
EQD
2,T
(Gy)
#Fractions
CRT
1326
42-63
20-43
SBRT
895
33-176
3-10
Protons
180
63-111
2-6
ESTRO
2017
Randomized phase III trials with proton therapy published as
of August 2017
Shipley et al., 1995