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0.2
0.3
0.4
0.5
0.6
0.7
0.8
0.9
1
0 1 2 3 4 5 6
Dose/Gy
Surviving fraction
αs
αr
S = e − αD − βD 2
α = αr 1 + αs αr − 1 ( ) e −D Dc ( )
Dc
Low-dose
hyper-
radiosensitivity
First reported in 1986 in
mouse epidermis and kidney
Short S, Mayes C, Woodcock M,
Johns H, Joiner MC.
Int J Radiat Biol 1999;75:847–55.
T98G human
GBM cells