How to measure normal tissue response?
•
Scoring of gross tissue effects
•
Scoring systems: grade the severity of tissue damage
using an arbitrary scale
•
Assays of tissue function
•
Functional assays to measure radiation effects
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E.g. blood counts as an indicator of bone marrow function
•
Clonogenic assays (L1.4)
•
Methods by which colony of cells that derive from a
single irradiated cell can be observed
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