Microsoft Word - RadBio_Programme_ParisSept2017_verAug31

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NHEJ

0

3

6

9

12

15

0.0001

0.001

0.01

0.1

1

Surviving fraction

Dose (Gy)

All tumors arising in

DNA-PK deficient

mice are

radiosensitive

Defects in EJ cause extreme

radiosensitivity