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ESTRO BCR Course / NT overall treatment time – W. Dörr
Changes in consequential late effects
Repopulation – clinical observations
EORTC 22851 - Mucositis Gr. 3+4
0
2
4
6
8
10
12
14
AF: 72 Gy / 45 F / 5 wk
CF: 70 Gy / 35 F / 7 wk
p=0.011
Gr. 3 mucosal late effects
- deep necrosis
- edema/tracheostomy
Fraction of patients [%]
data from: Horiot et al., RTO 44, 1997, 111-121