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Increased toxicity
No increased toxicity
Timmerman 2008
3
x 20 / 22 Gy
Joyner 2006
3
x 12 Gy
6
x 6 Gy
Song 2009
3-4
x 10-20 Gy
Senan 2007
8
x 7.5 Gy
Chang 2008
4
x 12.5 Gy
Guckenberger 2009
8
x 6 Gy
Milano 2009
10
x 3-5 Gy
Oshiro 2010
5
x 10 Gy
Is this „
EXCESSIVE TOXCITY
“ really unexpected
after RT with
EXCESSIVE DOSES
?
Risk adapted fractionation
M Guckenberger - SBRT stage I NSCLC - HICARE 2015
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