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BED

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Perscription dose PTV (Gy)

0.0

0.1

0.2

0.3

0.4

0.5

0.6

0.7

0.8

0.9

1.0

Local control

~105Gy

95% LC

Dose required to achieve local tumor control

Plateau of dose-response relationship at ~100Gy BED

RTOG

Guckenberger IJROBP 2008

Kerstin ASTRO Meeting 2010

M Guckenberger - SBRT stage I NSCLC - HICARE 2015

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