/
0
20
40
60
80 100 120 140 160 180 200
BED
10
Perscription dose PTV (Gy)
0.0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0.8
0.9
1.0
Local control
~105Gy
95% LC
Dose required to achieve local tumor control
Plateau of dose-response relationship at ~100Gy BED
RTOG
Guckenberger IJROBP 2008
Kerstin ASTRO Meeting 2010
M Guckenberger - SBRT stage I NSCLC - HICARE 2015
25