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Systematic review of SBRT for centrally located

NSCLC

M Guckenberger - SBRT stage I NSCLC - HICARE 2015

22

Publications

22

Centrally located tumors

563

Stage I NSCLC

315

LC for BED

100 Gy

85%

G 3 / 4 toxicity

9%

Overall Tx related mortality

2.7%

Tx related mortality BED <210Gy

1.0%

8 x 7.5Gy

5 x 10Gy

3 x 13Gy

• Acceptable therapeutic ratio of more fractionated SBRT