Folie 1

Study

# events

OAR

definition

Dose in patients with

radiation myelopathy

Conclusion

Ryu

2006

1 / 177

SC 6mm CC

of TV

9.6Gy to 10%

10% < 10Gy

Gibbs

2009

6 / 1075

max

8.5 – 26.2Gy

1cm

< 8Gy

Sahgal

2010

5 / 24

case control study

Thecal sack

max

median 59Gy (nBED

2/2

)

max

below

thresholds using

LQ model

Safety of spine SBRT: myelopathy

• (Very) Few patients developed radiation induced myelopathy

• Dose – response inconclusive

• However: follow-up short in majority of patients

SBRT for verterbal metastases - Matthias Guckenberger - 2014